Shark IgNAR-derived binding domains as potential diagnostic and therapeutic agents

H Matz, H Dooley - Developmental & Comparative Immunology, 2019 - Elsevier
Many of the most successful drugs generated in recent years are based upon monoclonal
antibodies (mAbs). However, for some therapeutic and diagnostic applications mAbs are far …

[HTML][HTML] Gentiopicroside (GENT) protects against sepsis induced by lipopolysaccharide (LPS) through the NF-κB signaling pathway

Q Wang, X Zhou, L Yang, M Luo, L Han… - Annals of …, 2019 - ncbi.nlm.nih.gov
Background Sepsis is a high-mortality disease without effective therapeutic options. The
hyperactivation of the monocyte-macrophage system, especially M1 macrophages, triggers …

Increased expression of Toll-like receptors 2, 3, 4 and 7 mRNA in the kidney and intestine of a septic mouse model

S Krivan, A Kapelouzou, S Vagios, DI Tsilimigras… - Scientific reports, 2019 - nature.com
Toll-like receptors (TLRs) are the key regulators of innate and adaptive immunity and are
highly expressed during sepsis. Thus, studying the expression of TLRs in an animal septic …

Lactate‐induced activation of HCA2 improves survival in mice with sepsis

A Takakura, K Zandi-Nejad - The FASEB Journal, 2019 - Wiley Online Library
Sepsis is characterized by systemic inflammation that is caused by infection and by
activation of proinflammatory pathways, resulting in mitochondrial and cellular dysfunction …

[HTML][HTML] PP2ACα of alveolar macrophages is a novel protective factor for LPS-induced acute respiratory distress syndrome

Z He, L Du, Y Ke, C Wen, Y Zhang - Inflammation, 2019 - Springer
Abstract Protein phosphatase 2A (PP2A) is one main serine/threonine phosphatase in
eukaryotes, and its activation changes have been linked to modulation of numerous …

Effect of cadmium on the concentration and expression of TNF-α protein in sea urchin Diadema setosum (Leske, 1778)

D Rumahlatu, A Duran-Corebima, M Amin… - Hidrobiológica, 2019 - scielo.org.mx
Resumen RUMAHLATU, Dominggus; DURAN-COREBIMA, Aloysius; AMIN, Mohamad y
ROHMAN, Fatchur. Effect of cadmium on the concentration and expression of TNF-α protein …

Yoğun Bakım Hastalarında Erken Enteral İmmünonütrisyon Uygulamasının Enflamatuvar Yanıta Etkisi.

F Çelik, İS Edipoğlu - Turkish Journal of Intensive Care, 2019 - search.ebscohost.com
Amaç: Erken enteral immünonütrisyon, sitokinlere bağlı oluşan stres yanıtta değişiklikler
oluşturarak, sistemik enflamatuvar yanıttan, sepsise doğru gelişen dinamik süreçte optimal …

Sterility and stability of diluted meloxicam in compounded multi-dose vial after 365 days

HK Kawano, GD Simonek, AD Moffitt… - Journal of the …, 2019 - ingentaconnect.com
Meloxicam is a common analgesic for rodents. Because meloxicam is only formulated
commercially for companion animals, it requires dilution to achieve doses appropriate for …

[引用][C] Ratlarda LPSnin kan dokusu üzerine akut etkisive sodyum selenit ve vitamin Enin koruyucurolü

Z İlçe - Fen Bilimleri Enstitüsü

[引用][C] Lipopolisakkarit ile oluşturulan septik şok ilişkili akut böbrek hasarında pioglitazonun etkisi

Ö Kaman - Tıp Fakültesi