Fast-acting antidepressant activity of ketamine: highlights on brain serotonin, glutamate, and GABA neurotransmission in preclinical studies

TH Pham, AM Gardier - Pharmacology & therapeutics, 2019 - Elsevier
Ketamine, a non-competitive antagonist of N-methyl-D-aspartate (NMDA) receptor, displays
a fast antidepressant activity in treatment-resistant depression and in rodent models of …

Risk assessment and serotonin: animal models and human psychopathologies

DC Blanchard, K Meyza - Behavioural brain research, 2019 - Elsevier
Risk assessment (RA) is an evolved, generally adaptive, mechanism comprising focused
attention and appraisal of potential threat stimuli and situations. Initially characterized in …

A shift in the activation of serotonergic and non-serotonergic neurons in the dorsal raphe lateral wings subnucleus underlies the panicolytic-like effect of fluoxetine in …

HH Vilela-Costa, A Spiacci, IG Bissolli… - Molecular …, 2019 - Springer
A wealth of evidence indicates that the lateral wings subnucleus of the dorsal raphe nucleus
(lwDR) is implicated in the processing of panic-associated stimuli. Escape expression in the …

Muscular and mitochondrial effects of long-term fluoxetine treatment in mice, combined with physical endurance exercise on treadmill

A Tutakhail, QA Nazari, S Khabil, A Gardier, F Coudore - Life sciences, 2019 - Elsevier
Aim Fluoxetine, one of the first newer SSRI antidepressant, is an extremely popular
treatment for depression that could improve mental health problems. Many recent studies …

Neural Circuits Associated with 5-HT1B Receptor Agonist Inhibition of Methamphetamine Seeking in the Conditioned Place Preference Model

TS Der-Ghazarian, D Charmchi… - ACS chemical …, 2019 - ACS Publications
5-HT1B receptors (5-HT1BRs) modulate psychostimulant reward and incentive motivation in
rodents. Here we investigated the effects of the 5-HT1BR agonist CP94253 (10 mg/kg, IP) on …

[PDF][PDF] Anabolic-androgenic steroids cycle administration decreases anxious-like behavior but does not affect long-term memory acquisition in rats

LFS de Oliveira, M Staudt, MM Machado… - Acta Scientiarum …, 2019 - redalyc.org
The steroid hormones are lipids in nature, which play crucial roles in several metabolic and
behavioral pathways in mammals. Drug therapy uses sterol hormones for treating some …