Designing paper-based immunoassays for biomedical applications

DR Hristov, C Rodriguez-Quijada, J Gomez-Marquez… - Sensors, 2019 - mdpi.com
Paper-based sensors and assays have been highly attractive for numerous biological
applications, including rapid diagnostics and assays for disease detection, food safety, and …

Target site delivery and residence of nanomedicines: Application of quantitative systems pharmacology

JLS Au, RA Abbiati, MG Wientjes, Z Lu - Pharmacological reviews, 2019 - ASPET
Quantitative systems pharmacology (QSP), an emerging field that entails using modeling
and computation to interpret, interrogate, and integrate drug effects spanning from the …

Lactoferrin adsorption onto silver nanoparticle interface: Implications of corona on protein conformation, nanoparticle cytotoxicity and the formulation adjuvanticity

PS Nayak, SM Borah, H Gogoi, S Asthana… - Chemical Engineering …, 2019 - Elsevier
Nanoparticle, in biological milieu, tends to bind a variety of biomolecules, especially protein,
forming an interfacial corona that provides biological identity to nanoparticle. Understanding …

Molecular interaction of fibrinogen with zeolite nanoparticles

H Derakhshankhah, A Hosseini, F Taghavi, S Jafari… - Scientific reports, 2019 - nature.com
Fibrinogen is one of the key proteins that participate in the protein corona composition of
many types of nanoparticles (NPs), and its conformational changes are crucial for activation …

Utilizing corona on functionalized selenium nanoparticles for loading and release of doxorubicin payload

D Chakraborty, P Chauhan, S Kumar… - Journal of molecular …, 2019 - Elsevier
Incorporation of nanoparticles in serum containing-media leads to spontaneous adsorption
of proteins on the nanoparticle surface thus forming “protein corona”. The current study …

Bimetallic gold nanorods with enhanced biocorona formation for doxorubicin loading and sustained release

D Chakraborty, L Mohan, SA Alex… - Biomaterials …, 2019 - pubs.rsc.org
The biomedical applicability of gold nanorods (AuNRs) arises due to their interesting optical
and photothermal properties, which can result in the formation of a protein corona layer …

A multi-spectroscopic approach to investigate the interactions between Gramicidin A and silver nanoparticles

M Gambucci, PL Gentili, P Sassi, L Latterini - Soft Matter, 2019 - pubs.rsc.org
The comprehension and control of the interactions between nanoparticles and proteins at a
molecular level are crucial to improve biomedical applications of nanomaterials and to …

Mapping molecular structure of protein locating on nanoparticles with limited proteolysis

Y Duan, Y Liu, R Coreas, W Zhong - Analytical chemistry, 2019 - ACS Publications
The molecular structure of a protein could be altered when it is attached to nanoparticles
(NPs), affecting the performance of NPs present in biological systems. Limited proteolysis …

[PDF][PDF] Molecular dynamics simulations: A tool to investigate the interactions between biomolecules and nanoparticles

S Rajkhowa, AN Jha - Nov Sci Publ Inc, 2019 - researchgate.net
Nanoparticles (NP) play a significant role in the biological system as they aid/accelerate the
drug delivery inside the cell. These selfassembling units have found applications in …

[PDF][PDF] Materials Today Advances

K Nienhaus, H Wang, GU Nienhaus - 2019 - scholar.archive.org
abstract Nanomaterials have high potential as powerful tools for nanomedicine in a wide
range of most promising applications as highly specific devices for diagnosis and therapy …