Phagocytosis checkpoints as new targets for cancer immunotherapy
Cancer immunotherapies targeting adaptive immune checkpoints have substantially
improved patient outcomes across multiple metastatic and treatment-refractory cancer types …
improved patient outcomes across multiple metastatic and treatment-refractory cancer types …
Inflammation and fibrosis in murine models of heart failure
L Bacmeister, M Schwarzl, S Warnke, B Stoffers… - Basic research in …, 2019 - Springer
Heart failure is a consequence of various cardiovascular diseases and associated with poor
prognosis. Despite progress in the treatment of heart failure in the past decades, prevalence …
prognosis. Despite progress in the treatment of heart failure in the past decades, prevalence …
Ginseng-derived nanoparticles alter macrophage polarization to inhibit melanoma growth
M Cao, H Yan, X Han, L Weng, Q Wei, X Sun… - … for immunotherapy of …, 2019 - Springer
Background It is unclear whether plant-derived extracellular vesicles (EVs) can mediate
interspecies communication with mammalian cells. Tumor-associated macrophages (TAMs) …
interspecies communication with mammalian cells. Tumor-associated macrophages (TAMs) …
Targeting cell signaling in allergic asthma
SS Athari - Signal transduction and targeted therapy, 2019 - nature.com
Asthma is chronic inflammation of the airways characterized by airway hyper-
responsiveness, wheezing, cough, and dyspnea. Asthma affects> 350 million people …
responsiveness, wheezing, cough, and dyspnea. Asthma affects> 350 million people …
Recent clinical trends in Toll‐like receptor targeting therapeutics
Toll‐like receptors (TLRs) are germline‐encoded receptors that are central to innate and
adaptive immune responses. Owing to their vital role in inflammation, TLRs are rational …
adaptive immune responses. Owing to their vital role in inflammation, TLRs are rational …
Transcriptome of extracellular vesicles: state-of-the-art
A Turchinovich, O Drapkina, A Tonevitsky - Frontiers in immunology, 2019 - frontiersin.org
Exosomes and microvesicles are two major categories of extracellular vesicles (EVs)
released by almost all cell types and are highly abundant in biological fluids. Both the …
released by almost all cell types and are highly abundant in biological fluids. Both the …
Urinary tract infection: Pathogenicity, antibiotic resistance and development of effective vaccines against Uropathogenic Escherichia coli
Urinary tract infections (UTIs) are recognized as one of the most common infectious
diseases in the world that can be divided to different types. Uropathogenic Escherichia coli …
diseases in the world that can be divided to different types. Uropathogenic Escherichia coli …
[HTML][HTML] Mechanisms and therapeutic targets of ischemic acute kidney injury
SJ Han, HT Lee - Kidney research and clinical practice, 2019 - ncbi.nlm.nih.gov
Acute kidney injury (AKI) due to renal ischemia reperfusion (IR) is a major clinical problem
without effective therapy and is a significant and frequent cause of morbidity and mortality …
without effective therapy and is a significant and frequent cause of morbidity and mortality …
[HTML][HTML] Effects of berberine and metformin on intestinal inflammation and gut microbiome composition in db/db mice
W Zhang, JH Xu, T Yu, QK Chen - Biomedicine & Pharmacotherapy, 2019 - Elsevier
Berberine and metformin, both established pharmaceutical agents with herbal origins, have
incidental beneficial effects on multiple diseases, including diabetes. These effects have …
incidental beneficial effects on multiple diseases, including diabetes. These effects have …
Psoriasis: keratinocytes or immune cells–which is the trigger?
F Benhadou, D Mintoff, V Del Marmol - Dermatology, 2019 - karger.com
Background: Psoriasis is a common, chronic inflammatory skin disorder, which can
significantly impact quality of life. Despite major breakthroughs in our understanding of the …
significantly impact quality of life. Despite major breakthroughs in our understanding of the …