[HTML][HTML] ctDNA applications and integration in colorectal cancer: an NCI Colon and Rectal–Anal Task Forces whitepaper

A Dasari, VK Morris, CJ Allegra, C Atreya… - Nature reviews Clinical …, 2020 - nature.com
An increasing number of studies are describing potential uses of circulating tumour DNA
(ctDNA) in the care of patients with colorectal cancer. Owing to this rapidly developing area …

Liquid biopsy in the clinical management of hepatocellular carcinoma

J von Felden, T Garcia-Lezana, K Schulze, B Losic… - Gut, 2020 - gut.bmj.com
With increasing knowledge on molecular tumour information, precision oncology has
revolutionised the medical field over the past years. Liquid biopsy entails the analysis of …

ctDNA monitoring using patient-specific sequencing and integration of variant reads

JCM Wan, K Heider, D Gale, S Murphy… - Science translational …, 2020 - science.org
Circulating tumor-derived DNA (ctDNA) can be used to monitor cancer dynamics
noninvasively. Detection of ctDNA can be challenging in patients with low-volume or …

[HTML][HTML] Clonal hematopoiesis in liquid biopsy: from biological noise to valuable clinical implications

HT Chan, YM Chin, Y Nakamura, SK Low - Cancers, 2020 - mdpi.com
The use of blood liquid biopsy is being gradually incorporated into the clinical setting of
cancer management. The minimally invasive nature of the usage of cell-free DNA (cfDNA) …

[HTML][HTML] Early stage colon cancer: Current treatment standards, evolving paradigms, and future directions

S Chakrabarti, CY Peterson, D Sriram… - World journal of …, 2020 - ncbi.nlm.nih.gov
Colon cancer continues to be one of the leading causes of mortality and morbidity
throughout the world despite the availability of reliable screening tools and effective …

[HTML][HTML] Adjuvant chemotherapy for stage III colon cancer

J Taieb, C Gallois - Cancers, 2020 - mdpi.com
Simple Summary In patients with stage III colon cancer, adjuvant chemotherapy with a
fluoropyrimidine combined with oxaliplatin reduces the risk of recurrence and mortality, with …

[HTML][HTML] Adjuvant chemotherapy for stage II colon cancer

SE Rebuzzi, G Pesola, V Martelli, AF Sobrero - Cancers, 2020 - mdpi.com
Simple Summary Stage II colon cancer is defined as an early stage of the tumor disease,
without the involvement of lymph nodes or distant organs. In this group of patients, surgery …

[HTML][HTML] The promise of circulating tumor DNA (ctDNA) in the management of early-stage colon cancer: a critical review

S Chakrabarti, H Xie, R Urrutia, A Mahipal - Cancers, 2020 - mdpi.com
Simple Summary Currently, the treatment for localized colon cancer consists of surgery and,
if the presence of residual cancer cells is suspected, chemotherapy following the surgery …

Perspectives of the application of liquid biopsy in colorectal cancer

Y Ding, W Li, K Wang, C Xu, M Hao… - BioMed Research …, 2020 - Wiley Online Library
Colorectal cancer (CRC) is one of the most common gastrointestinal tumors and the second
leading cause of cancer death worldwide. Since traditional biopsies are invasive and do not …

[HTML][HTML] Circulating tumor DNA in colorectal cancer: opportunities and challenges

F Bi, Q Wang, Q Dong, Y Wang, L Zhang… - American journal of …, 2020 - ncbi.nlm.nih.gov
Tumor biopsy is the standard method for cancer diagnosis and provides an important
sample for pathological assessment. With the development of precision medicine, liquid …