An update review on the Paneth cell as key to ileal Crohn's disease

J Wehkamp, EF Stange - Frontiers in immunology, 2020 - frontiersin.org
The Paneth cells reside in the small intestine at the bottom of the crypts of Lieberkühn,
intermingled with stem cells, and provide a niche for their neighbors by secreting growth and …

Adherent-Invasive E. coli: Update on the Lifestyle of a Troublemaker in Crohn's Disease

M Chervy, N Barnich, J Denizot - International Journal of Molecular …, 2020 - mdpi.com
Besides genetic polymorphisms and environmental factors, the intestinal microbiota is an
important factor in the etiology of Crohn's disease (CD). Among microbiota alterations, a …

Adaptation of adherent-invasive E. coli to gut environment: Impact on flagellum expression and bacterial colonization ability

G Sevrin, S Massier, B Chassaing, A Agus… - Gut …, 2020 - Taylor & Francis
The pathogenesis of Crohn's disease (CD) is multifactorial and involves genetic
susceptibility, environmental triggers and intestinal microbiota. Adherent-invasive …

Sodium houttuyfonate enhances the intestinal barrier and attenuates inflammation induced by Salmonella typhimurium through the NF-κB pathway in mice

L Zhang, H Lv, Y Li, N Dong, C Bi, A Shan, Z Wu… - International …, 2020 - Elsevier
Salmonella typhimurium (ST), as an aggressive bacterium, mainly causes intestinal
inflammation and diarrhea. Sodium houttuyfonate (SH) is a derivative of houttuynin in the …

Conserved regulation of omptin proteases by the PhoPQ two-component regulatory system in Enterobacteriaceae

YH Cho, MRF Aziz, T Sutradhar, J Bashal, V Cojocari… - bioRxiv, 2020 - biorxiv.org
Bacteria that colonize eukaryotic surfaces interact with numerous host-produced molecules
that have antimicrobial activity. Bacteria have evolved numerous strategies to both detect …

[PDF][PDF] HYPERGLYCEMIA AND COMPONENTS OF AN OBESOGENIC DIET WORSEN THE OUTCOMES OF ENTERIC INFECTION

T Lau - 2020 - macsphere.mcmaster.ca
Obesity is a major predictor for type 2 diabetes. The etiology and comorbidities of these two
diseases are associated. Diabetics are twice as likely to contract any type of infection and at …

Tackling bacterial pathogenesis: a transcriptional regulator as novel target for antivirulence therapy

V Lucchini - 2020 - edoc.unibas.ch
The lack of antibiotics and the alarming spread of multi-drug resistant (MDR) bacteria is
currently leaving clinicians with very limited options to combat infectious diseases as still …