Codon usage and splicing jointly influence mRNA localization

C Mordstein, R Savisaar, RS Young, J Bazile… - Cell systems, 2020 - cell.com
In the human genome, most genes undergo splicing, and patterns of codon usage are
splicing dependent: guanine and cytosine (GC) content is the highest within single-exon …

Transduction optimization of AAV vectors for human gene therapy of glaucoma and their reversed cell entry characteristics

L Rodriguez-Estevez, P Asokan, T Borrás - Gene therapy, 2020 - nature.com
The trabecular meshwork (TM) of the eye is responsible for maintaining physiological
intraocular pressure (IOP). Dysfunction of this tissue results in elevated IOP, subsequent …

Slowly folding surface extension in the prototypic avian hepatitis B virus capsid governs stability

C Makbul, M Nassal, B Böttcher - Elife, 2020 - elifesciences.org
Hepatitis B virus (HBV) is an important but difficult to study human pathogen. Most basics of
the hepadnaviral life-cycle were unraveled using duck HBV (DHBV) as a model although …

Methods of packaging multiple adeno-associated virus vectors

BJ Byrne, PA Doerfler, N Clement - US Patent 10,781,459, 2020 - Google Patents
US10781459B2 - Methods of packaging multiple adeno-associated virus vectors - Google
Patents US10781459B2 - Methods of packaging multiple adeno-associated virus vectors …

[引用][C] Untersuchungen zur Proteom-basierten Aufklärung einer durch Adenovirus 5 E4orf6 Protein vermittelten Interferenz mit der Hepadnavirus Replikation

J Miller - 2020 - Dissertation, Universität Freiburg …