An exosome-like programmable-bioactivating paclitaxel prodrug nanoplatform for enhanced breast cancer metastasis inhibition

K Wang, H Ye, X Zhang, X Wang, B Yang, C Luo… - Biomaterials, 2020 - Elsevier
Metastasis is closely associated with high breast cancer mortality. Although nanotechnology-
based anti-metastatic treatments have developed rapidly, the anti-metastasis efficiency is …

Microenvironment‐induced TIMP2 loss by cancer‐secreted exosomal miR‐4443 promotes liver metastasis of breast cancer

J Wang, Q Zhang, D Wang, S Yang… - Journal of Cellular …, 2020 - Wiley Online Library
We aimed to investigate the role of exosomal miR‐4443 in metastasis of breast cancer
(BCa). In vitro wound‐healing assay and transwell invasion assay were used to investigate …

OIP5‑AS1 modulates epigenetic regulator HDAC7 to enhance non‑small cell lung cancer metastasis via miR‑140‑5p

J Mei, G Liu, W Wang, P Xiao, D Yang… - Oncology …, 2020 - spandidos-publications.com
Long non‑coding RNAs have been reported to be involved in non‑small cell lung cancer
(NSCLC) progression. However, whether Opa‑interacting protein 5 antisense RNA 1 (OIP5 …

Oridonin exhibits anti-angiogenic activity in human umbilical vein endothelial cells by inhibiting VEGF-induced VEGFR-2 signaling pathway

JH Jiang, J Pi, JY Cai - Pathology-Research and Practice, 2020 - Elsevier
Oridonin has been found to be a potential anti-angiogenesis agent. However, its functional
targets and the underlying mechanisms are still vague. In vitro studies we found that …

[HTML][HTML] Limonin inhibits angiogenesis and metastasis of human breast cancer cells by suppressing the VEGFR2/IGFR1-mediated STAT3 signaling pathway

J Chen, BX Liu, Q Shen, N Li, J Ling… - Translational cancer …, 2020 - ncbi.nlm.nih.gov
Background Limonin is one of the major active ingredients of citrus. In the present study, the
anti-angiogenic and anti-metastatic effects of limonin were investigated. Methods The …

In vitro and in vivo evaluation of gentamicin sulphate-loaded PLGA nanoparticle-based film for the treatment of surgical site infection

C Dhal, R Mishra - Drug Delivery and Translational Research, 2020 - Springer
The study focuses on the in vitro and in vivo evaluation of the developed gentamicin
sulphate (GS)-loaded poly lactic-co-glycolic acid (PLGA) nanoparticle (PNP)-based pullulan …

[图书][B] Exploring the Roles of Long Non-Coding RNAs in Glioblastoma Tumor Recurrence and Therapy Resistance

CT Stackhouse - 2020 - search.proquest.com
Glioblastoma (GBM) is the most common and devastating primary CNS brain tumor with a
median survival time of around 14 months. Most patients succumb to re-current disease …

Momordica charantia bitkisinin içerdiği triterpenlerin vaskülarizasyonda görevli proteinlerle etkileşimlerinin in silico olarak değerlendirilmesi

B Sevim - 2020 - acikkaynak.bilecik.edu.tr
Anjiyogenez; tümör oluşum sürecinde yer alan oldukça önemli bir süreçtir. Bu süreçte yer
alan ve tirozin kinaz reseptör ailesinin bir üyesi olan VEGFR1, tümör hücrelerinde VEGFA …