[HTML][HTML] Successes and challenges in simulating the folding of large proteins
A Gershenson, S Gosavi, P Faccioli… - Journal of Biological …, 2020 - ASBMB
Computational simulations of protein folding can be used to interpret experimental folding
results, to design new folding experiments, and to test the effects of mutations and small …
results, to design new folding experiments, and to test the effects of mutations and small …
Experimentally-driven protein structure modeling
NV Dokholyan - Journal of proteomics, 2020 - Elsevier
Revolutions in natural and exact sciences started at the dawn of last century have led to the
explosion of theoretical, experimental, and computational approaches to determine …
explosion of theoretical, experimental, and computational approaches to determine …
Glassy dynamics and memory effects in an intrinsically disordered protein construct
Glassy, nonexponential relaxations in globular proteins are typically attributed to
conformational behaviors that are missing from intrinsically disordered proteins. Yet, we …
conformational behaviors that are missing from intrinsically disordered proteins. Yet, we …
The complexity of protein structure and the challenges it poses in developing biopharmaceuticals
SA Berkowitz, DJ Houde - Biophysical Characterization of Proteins in …, 2020 - Elsevier
In this chapter the key elements and characteristics of what constitutes the structure of a
protein, along with the associated nomenclature are reviewed. Next, the unique structural …
protein, along with the associated nomenclature are reviewed. Next, the unique structural …
Protein folding and structure prediction: biological and physical perspectives
MA Chonofsky - 2020 - ora.ox.ac.uk
Protein folding is poorly understood and distinct from protein structure prediction,
encompassing the translation and folding process of proteins in vivo and in vitro. In this …
encompassing the translation and folding process of proteins in vivo and in vitro. In this …