Sex differences in post-traumatic stress disorder risk: autonomic control and inflammation

IT Fonkoue, V Michopoulos, J Park - Clinical Autonomic Research, 2020 - Springer
Aim Over 7 million US adults and about 20% of the military population have post-traumatic
stress disorder (PTSD), a debilitating condition that is independently linked to a significantly …

The role of the genome in experience-dependent plasticity: Extending the analogy of the genomic action potential

DF Clayton, I Anreiter, M Aristizabal… - Proceedings of the …, 2020 - National Acad Sciences
Our past experiences shape our current and future behavior. These experiences must leave
some enduring imprint on our brains, altering neural circuits that mediate behavior and …

[HTML][HTML] Cross-platform comparison of highly sensitive immunoassay technologies for cytokine markers: Platform performance in post-traumatic stress disorder and …

HC Lasseter, AC Provost, LE Chaby, NP Daskalakis… - Cytokine: X, 2020 - Elsevier
There is mounting evidence of systemic inflammation in post-traumatic stress disorder
(PTSD) and Parkinson's disease (PD), yet inconsistency and a lack of replicability in findings …

Increased H3K4me3 methylation and decreased miR-7113-5p expression lead to enhanced Wnt/β-catenin signaling in immune cells from PTSD patients leading to …

M Bam, X Yang, BP Busbee, AE Aiello, M Uddin… - Molecular …, 2020 - Springer
Background Posttraumatic stress disorder (PTSD) is a psychiatric disorder accompanied by
chronic peripheral inflammation. What triggers inflammation in PTSD is currently unclear. In …

Mapping PTSD symptoms to brain networks: a machine learning study

A Zandvakili, J Barredo, HR Swearingen… - Translational …, 2020 - nature.com
Abstract Posttraumatic Stress Disorder (PTSD) is a prevalent and debilitating condition with
complex and variable presentation. While PTSD symptom domains (intrusion, avoidance …

Sacrificing reward to avoid threat: Characterizing PTSD in the context of a trauma-related approach–avoidance conflict task.

SS Weaver, EB Kroska, MC Ross… - Journal of Abnormal …, 2020 - psycnet.apa.org
Posttraumatic stress disorder (PTSD) is characterized by heightened avoidance, cognitive
inflexibility, and impaired reward processing. Maladaptive behavior in PTSD may reflect an …

Neuroimmune mechanisms and sex/gender-dependent effects in the pathophysiology of mental disorders

AG Kokkosis, SE Tsirka - Journal of Pharmacology and Experimental …, 2020 - ASPET
Innate and adaptive immune mechanisms have emerged as critical regulators of CNS
homeostasis and mental health. A plethora of immunologic factors have been reported to …

Nervous and endocrine system dysfunction in posttraumatic stress disorder: An overview and consideration of sex as a biological variable

AV Seligowski, NG Harnett, JB Merker… - Biological Psychiatry …, 2020 - Elsevier
Decades of research into the biological mechanisms of posttraumatic stress disorder (PTSD)
suggests that chronic activation of the stress response leads to long-lasting changes in the …

Plasma Lipidomic Analyses in Cohorts With mTBI and/or PTSD Reveal Lipids Differentially Associated With Diagnosis and APOE ε4 Carrier Status

CJC Huguenard, A Cseresznye, JE Evans… - Frontiers in …, 2020 - frontiersin.org
The differential diagnosis between mild Traumatic Brain Injury (mTBI) sequelae and Post-
Traumatic Stress Disorder (PTSD) is challenging due to their symptomatic overlap and co …

Trauma exposure and stress‐related disorders in African‐American women with diabetes mellitus

HD Dixon, V Michopoulos, RL Gluck… - Endocrinology …, 2020 - Wiley Online Library
Objective The purpose of the study was to assess demographic features, rates of trauma
exposure, prevalence of post‐traumatic stress and depressive symptoms in a group of …