Ecological concerns have recently led to the increasing trend to upgrade carbon contained
in waste streams into valuable chemicals. One of these components is acetate. Its microbial …

Desiccation is a common stress that bacteria face in the natural environment, and thus, they
have developed a variety of protective mechanisms to mitigate the damage caused by water …

Lysine acetylation (Kac), an abundant post-translational modification (PTM) in prokaryotes,
regulates various microbial metabolic pathways. However, no studies have examined …

Reversible lysine acetylation (RLA) of translation machinery components, such as ribosomal
proteins (RPs) and translation factors (TFs), was identified in many microorganisms, while …

Protein lysine acetylation, one of the most abundant post-translational modifications in
eukaryotes, occurs in prokaryotes as well. Despite the evidence of lysine acetylation in …

Post-translational modifications of proteins enable swift physiological adaptation of cells to
altered growth conditions and stress. Aside from protein phosphorylation, acetylation on ε …

Motivation Enzymatic digestion of proteins before mass spectrometry analysis is a key
process in metaproteomic workflows. Canonical metaproteomic data processing pipelines …

Lys deacylases are essential regulators of cell biology in many contexts. Here, we have
identified CddA (cyanobacterial deacetylase/depropionylase), a Lys deacylase enzyme …

Fluctuating environments force bacteria to constantly adapt and optimize the uptake of
substrates to maintain cellular and nutritional homeostasis. Our recent findings revealed that …

Francisella tularensis is a Gram-negative bacterium that causes the zoonotic disease
tularemia. The historical development of tularemia as a biological weapon has led to it being …