Severe refractory asthma (SRA) still has a high economic and social impact, including a
reduction in quality of life (QoL), productivity, a greater risk of exacerbations and emergency …

The gastrointestinal tract, the second largest organ in the body, plays an important role in
nutrient and mineral intake through the intestinal barrier. Dysfunction of intestinal …

Background Asthma, a common chronic inflammatory disease, is treated with corticosteroid
in most cases, but corticosteroid resistance in severe asthma patients seriously impairs the …

Abstract Ethnopharmacological relevance Shegan-Mahuang Decoction (SMD), also named
Yakammaoto or Shegan-Mahuang Tang, is a classic formula of traditional Chinese medicine …

Background Eugenol, a common phenylpropanoid derivative found in different plant
species, has well-described anti-inflammatory effects associated with the development of …

Background Glucocorticoid (GC) insensitivity is an important feature of severe and fatal
asthma. Oxidative stress can induce phosphoinositide-3-kinase (PI3K) activation …

Since the announcement by the World Health Organization (WHO) of an outbreak of a
contagious respiratory viral pneumonia in Wuhan, China, in December 2019 (later named …

Background Relapses in steroid‐responsive meningitis‐arteritis (SRMA) are frequently
observed but specific treatment protocols to address this problem are sparsely reported …

There is a large interindividual variability in response to ICSs in asthma. About 70% of the
variance in ICS response is likely due at least partially to genetically determined …

Objective This study aimed to investigate the clinical characteristics and risk factors
associated with severe pneumonia in systemic lupus erythematosus (SLE) patients from …