[HTML][HTML] A review on the pharmacokinetics of paeoniflorin and its anti-inflammatory and immunomodulatory effects

YX Zhou, XH Gong, H Zhang, C Peng - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Increasing pharmacological evidence supports that paeoniflorin, a water-soluble
monoterpene glycoside isolated from Paeonia lactiflora Pall.(Shaoyao in Chinese), has a …

[HTML][HTML] Modulation of exercise-induced muscle damage, inflammation, and oxidative markers by curcumin supplementation in a physically active population: a …

D Fernández-Lázaro, J Mielgo-Ayuso, J Seco Calvo… - Nutrients, 2020 - mdpi.com
Physical activity, particularly high-intensity eccentric muscle contractions, produces exercise-
induced muscle damage (EIMD). The breakdown of muscle fibers and the consequent …

Impact of curcumin supplementation on expression of inflammatory transcription factors in hemodialysis patients: A pilot randomized, double-blind, controlled study

L Alvarenga, R Salarolli, LFMF Cardozo, RS Santos… - Clinical Nutrition, 2020 - Elsevier
Background & aims Chronic kidney disease (CKD) patients have numerous complications
associated with inflammation, which is a potential driver for cardiovascular disease …

Curcumin downregulates the PI3K–AKT–mTOR pathway and inhibits growth and progression in head and neck cancer cells

GA Borges, ST Elias, B Amorim… - Phytotherapy …, 2020 - Wiley Online Library
Curcumin, a polyphenol isolated from the rhizome of Curcuma longa, has been studied
because of its antioxidant, antimicrobial, and antiinflammatory properties. This study aimed …

[HTML][HTML] Nature-derived compounds modulating Wnt/β-catenin pathway: a preventive and therapeutic opportunity in neoplastic diseases

G Sferrazza, M Corti, G Brusotti, P Pierimarchi… - … Pharmaceutica Sinica B, 2020 - Elsevier
The Wnt/β-catenin signaling is a conserved pathway that has a crucial role in embryonic and
adult life. Dysregulation of the Wnt/β-catenin pathway has been associated with diseases …

Targeting the Wnt/β-catenin pathway in neurodegenerative diseases: recent approaches and current challenges

A Serafino, D Giovannini, S Rossi… - Expert Opinion on Drug …, 2020 - Taylor & Francis
Introduction Wnt/β-catenin signaling is an evolutionarily conserved pathway having a crucial
role in embryonic and adult life. Specifically, the Wnt/β-catenin axis is pivotal to the …

[HTML][HTML] Curcumin: could this compound be useful in pregnancy and pregnancy-related complications?

T Filardi, R Varì, E Ferretti, A Zicari, S Morano… - Nutrients, 2020 - mdpi.com
Curcumin, the main polyphenol contained in turmeric root (Curcuma longa), has played a
significant role in medicine for centuries. The growing interest in plant-derived substances …

Alleviation of heat stress in broiler chicken using turmeric (Curcuma longa)-a short review

S Sugiharto - Journal of Animal Behaviour and Biometeorology, 2020 - jabbnet.com
Heat stress is one of the most crucial issues in broiler production, particularly in tropical
regions. Thermal stress may pose several problems related to growth, feed intake, nutrient …

Curcumin treatment attenuates alcohol-induced alterations in a mouse model of foetal alcohol spectrum disorders

L Cantacorps, S Montagud-Romero… - Progress in Neuro …, 2020 - Elsevier
Alcohol exposure during development produces physical and mental abnormalities in the
foetus that result in long-term molecular adjustments in the brain, which could underlie the …

[HTML][HTML] Curcumin induces regeneration of β cells and suppression of phosphorylated-NF-κB in streptozotocin-induced diabetic mice

AM Badr, H Sharkawy, AA Farid, S El-Deeb - The Journal of Basic and …, 2020 - Springer
Objectives This study aimed to assess the immunomodulatory effect of curcumin on innate
and adaptive immune responses, as well as its inhibitory power on hyperglycemia in …