Alzheimer's Disease (AD) therapeutics based on the amyloid hypothesis have repeatedly
failed in clinical trials. Together with numerous reports that amyloid is present in brains from …

TBI (traumatic brain injury) is a major cause of death among youth in industrialized societies.
Brain damage following traumatic injury is a result of direct and indirect mechanisms; …

Highly sensitive and specific plasma biomarkers for Alzheimer's disease (AD) have the
potential to improve diagnostic accuracy in the clinic and facilitate research studies including …

Current technologies for the point-of-care diagnosis of traumatic brain injury (TBI) lack
sensitivity, require specialist handling or involve complicated and costly procedures. Here …

Brain injury exosomal proteins are promising blood biomarker candidates in traumatic brain
injury (TBI). A better understanding of their role in the diagnosis, characterization, and …

Objective To determine whether blood-based biomarkers can differentiate older veterans
with and without traumatic brain injury (TBI) and cognitive impairment (CogI). Methods We …

The diagnosis and prognosis of traumatic brain injury (TBI) is complicated by variability in
the type and severity of injuries and the multiple endophenotypes that describe each …

Extracellular vesicles (EVs) have emerged as key mediators of cell-cell communication
during homeostasis and in pathology. Central nervous system (CNS)-derived EVs contain …

Background and Objectives: The annual global incidence of traumatic brain injury (TBI) is
over 10 million. An estimated 29% of TBI patients with negative computed tomography (CT−) …

Status epilepticus (SE) is a neurologic emergency with high morbidity and mortality. The
assessment of a patient's prognosis is crucial in making treatment decisions. In this review …