The “other” 15–40%: the role of non‐collagenous extracellular matrix proteins and minor collagens in tendon
N Taye, SZ Karoulias… - Journal of Orthopaedic …, 2020 - Wiley Online Library
Extracellular matrix (ECM) determines the physiological function of all tissues, including
musculoskeletal tissues. In tendon, ECM provides overall tissue architecture, which is …
musculoskeletal tissues. In tendon, ECM provides overall tissue architecture, which is …
[HTML][HTML] The ADAMTS/fibrillin connection: insights into the biological functions of ADAMTS10 and ADAMTS17 and their respective sister proteases
SZ Karoulias, N Taye, S Stanley, D Hubmacher - Biomolecules, 2020 - mdpi.com
Secreted ad isintegrin-like a nd m etalloprotease with t hrombo s pondin type 1 motif
(ADAMTS) proteases play crucial roles in tissue development and homeostasis. The …
(ADAMTS) proteases play crucial roles in tissue development and homeostasis. The …
A novel ADAMTS17 variant that causes Weill-Marchesani syndrome 4 alters fibrillin-1 and collagen type I deposition in the extracellular matrix
SZ Karoulias, A Beyens, Z Balic, S Symoens… - Matrix Biology, 2020 - Elsevier
Weill-Marchesani syndrome (WMS) is a rare genetic disorder that affects the
musculoskeletal system, the eye, and the cardiovascular system. Individuals with WMS …
musculoskeletal system, the eye, and the cardiovascular system. Individuals with WMS …
ADAMTS proteins: concepts, challenges, and prospects
SS Apte - ADAMTS Proteases: Methods and Protocols, 2020 - Springer
The ADAMTS superfamily comprises secreted metalloproteases (ADAMTS proteases) as
well as structurally related secreted glycoproteins that lack catalytic activity (ADAMTS-like …
well as structurally related secreted glycoproteins that lack catalytic activity (ADAMTS-like …
Alizarin red and alcian blue preparations to visualize the skeleton
TJ Mead - ADAMTS Proteases: methods and protocols, 2020 - Springer
Understanding proteolytic remodeling of extracellular matrix involves the generation of
global or conditional knockout mice by homologous recombination in embryonic stem cells …
global or conditional knockout mice by homologous recombination in embryonic stem cells …
Expression analysis by RNAscope™ in situ hybridization
TJ Mead, SS Apte - ADAMTS Proteases: Methods and Protocols, 2020 - Springer
RNA in situ hybridization has an important place in matrix biology, as the only method that
allows for in situ discrimination of precise spatial and temporal patterns of gene expression …
allows for in situ discrimination of precise spatial and temporal patterns of gene expression …
ADAMTS7 degrades Comp to fuel BMP2‐dependent osteogenic differentiation and ameliorate oncogenic potential in osteosarcomas
C Wang, Y Chen, H Xiang, X Wu, Q Tang, X Ma… - FEBS Open …, 2020 - Wiley Online Library
Osteosarcoma (OS) is the most common primary malignant bone tumor in children and
adolescents, with a high metastatic potential. Despite dramatic changes in OS treatments …
adolescents, with a high metastatic potential. Despite dramatic changes in OS treatments …
ADAMTS7: recombinant protein expression and purification
R de Groot - ADAMTS Proteases: Methods and Protocols, 2020 - Springer
ADAMTS7 is a secreted protease that is predominantly expressed in tissues of the
cardiovascular system and tendon. Although recent evidence suggests that it may play a …
cardiovascular system and tendon. Although recent evidence suggests that it may play a …