[HTML][HTML] The neuroscience of sadness: A multidisciplinary synthesis and collaborative review
Sadness is typically characterized by raised inner eyebrows, lowered corners of the mouth,
reduced walking speed, and slumped posture. Ancient subcortical circuitry provides a …
reduced walking speed, and slumped posture. Ancient subcortical circuitry provides a …
The Netrin-1/DCC guidance system: dopamine pathway maturation and psychiatric disorders emerging in adolescence
Axon guidance molecules direct growing axons toward their targets, assembling the intricate
wiring of the nervous system. One of these molecules, Netrin-1, and its receptor, DCC …
wiring of the nervous system. One of these molecules, Netrin-1, and its receptor, DCC …
A major role for common genetic variation in anxiety disorders
Anxiety disorders are common, complex psychiatric disorders with twin heritabilities of 30–
60%. We conducted a genome-wide association study of Lifetime Anxiety Disorder (n case …
60%. We conducted a genome-wide association study of Lifetime Anxiety Disorder (n case …
The genetics of the mood disorder spectrum: genome-wide association analyses of more than 185,000 cases and 439,000 controls
JRI Coleman, HA Gaspar, J Bryois, EM Byrne… - Biological …, 2020 - Elsevier
Background Mood disorders (including major depressive disorder and bipolar disorder)
affect 10% to 20% of the population. They range from brief, mild episodes to severe …
affect 10% to 20% of the population. They range from brief, mild episodes to severe …
Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank
Depression is more frequent among individuals exposed to traumatic events. Both trauma
exposure and depression are heritable. However, the relationship between these traits …
exposure and depression are heritable. However, the relationship between these traits …
Common genetic risk variants identified in the SPARK cohort support DDHD2 as a candidate risk gene for autism
Autism spectrum disorder (ASD) is a highly heritable neurodevelopmental disorder. Large
genetically informative cohorts of individuals with ASD have led to the identification of a …
genetically informative cohorts of individuals with ASD have led to the identification of a …
Genetic contributions to two special factors of neuroticism are associated with affluence, higher intelligence, better health, and longer life
Higher scores on the personality trait of neuroticism, the tendency to experience negative
emotions, are associated with worse mental and physical health. Studies examining links …
emotions, are associated with worse mental and physical health. Studies examining links …
Associations among monoamine neurotransmitter pathways, personality traits, and major depressive disorder
X Shao, G Zhu - Frontiers in psychiatry, 2020 - frontiersin.org
Major depressive disorder (MDD) is a complex psychiatric disease requiring
multidisciplinary approaches to identify specific risk factors and establish more efficacious …
multidisciplinary approaches to identify specific risk factors and establish more efficacious …
The Netrin-1/DCC guidance cue pathway as a molecular target in depression: translational evidence
The Netrin-1/DCC guidance cue pathway plays a critical role in guiding growing axons
toward the prefrontal cortex during adolescence and in the maturational organization and …
toward the prefrontal cortex during adolescence and in the maturational organization and …
Molecular genetics in psychology and personality neuroscience: On candidate genes, genome wide scans, and new research strategies
Despite the substantial heritability estimates for psychological traits, their precise genetic
foundation from a molecular perspective remains elusive. We summarize findings and …
foundation from a molecular perspective remains elusive. We summarize findings and …