A review on anti-cancer properties of Quercetin in breast cancer

M Ezzati, B Yousefi, K Velaei, A Safa - Life sciences, 2020 - Elsevier
Breast cancer is one of the well-known malignant tumors among women. In spite of attempts
to classifying breast cancer according to its histological and molecular properties, it is almost …

The therapeutic potential of anthocyanins: current approaches based on their molecular mechanism of action

B Salehi, J Sharifi-Rad, F Cappellini, Ž Reiner… - Frontiers in …, 2020 - frontiersin.org
Anthocyanins are natural phenolic pigments with biological activity. They are well-known to
have potent antioxidant and antiinflammatory activity, which explains the various biological …

Medicinal chemistry strategies to discover P-glycoprotein inhibitors: An update

J Dong, Z Qin, WD Zhang, G Cheng, AG Yehuda… - Drug Resistance …, 2020 - Elsevier
The presence of multidrug resistance (MDR) in malignant tumors is one of the primary
causes of treatment failure in cancer chemotherapy. The overexpression of the ATP binding …

Potential implications of quercetin and its derivatives in cardioprotection

K Ferenczyova, B Kalocayova, M Bartekova - International journal of …, 2020 - mdpi.com
Quercetin (QCT) is a natural polyphenolic compound enriched in human food, mainly in
vegetables, fruits and berries. QCT and its main derivatives, such as rhamnetin, rutin …

Flavonoid nanoparticles: A promising approach for cancer therapy

M Dobrzynska, M Napierala, E Florek - Biomolecules, 2020 - mdpi.com
Flavonoids, a ubiquitous group of naturally occurring polyphenolic compounds, have
recently gained importance as anticancer agents. Unfortunately, due to low solubility …

Flavonoids targeting NRF2 in neurodegenerative disorders

H Khan, R Tundis, H Ullah, M Aschner, T Belwal… - Food and Chemical …, 2020 - Elsevier
Neurodegenerative disorders are characterized by progressive loss of neurons. To date, no
efficacious therapies exist for these disorders, and current therapies provide only …

Seaweed-based natural ingredients: Stability of phlorotannins during extraction, storage, passage through the gastrointestinal tract and potential incorporation into …

L Cassani, A Gomez-Zavaglia, C Jimenez-Lopez… - Food Research …, 2020 - Elsevier
Adding value to seaweed by extracting their different bioactive compounds and
incorporating them into foods represent an interesting and strategic approach to diversify the …

Comprehensive Metabolome Analysis of Fermented Aqueous Extracts of Viscum album L. by Liquid Chromatography−High Resolution Tandem Mass Spectrometry

E Peñaloza, C Holandino, C Scherr, PIP Araujo… - Molecules, 2020 - mdpi.com
Fermented aqueous extracts of Viscum album L. are widely used for cancer treatment in
complementary medicine. The high molecular weight compounds viscotoxins and lectins are …

Neural underpinnings of obesity: the role of oxidative stress and inflammation in the brain

CA Mullins, RB Gannaban, MS Khan, H Shah… - Antioxidants, 2020 - mdpi.com
Obesity prevalence is increasing at an unprecedented rate throughout the world, and is a
strong risk factor for metabolic, cardiovascular, and neurological/neurodegenerative …

Protective effects of polyphenols against ischemia/reperfusion injury

M Cebova, O Pechanova - Molecules, 2020 - mdpi.com
Myocardial infarction (MI) is a leading cause of morbidity and mortality across the world. It
manifests as an imbalance between blood demand and blood delivery in the myocardium …