Prostate cancer (PrCa) ranks among the top five cancers for both incidence and mortality
worldwide. A significant proportion of PrCa susceptibility has been attributed to inherited …

PURPOSE Germline testing (GT) is a central feature of prostate cancer (PCA) treatment,
management, and hereditary cancer assessment. Critical needs include optimized …

Prostate cancer (PCa) is recognized as a disease possessing not only great variation in its
geographic and racial distribution but also tremendous variation in its potential to cause …

Men of predominantly African Ancestry (AA) have higher prostate cancer (CaP) incidence
and worse survival than men of predominantly European Ancestry (EA). While …

Known risk variants explain only a small proportion of breast cancer heritability, particularly
in Asian women. To search for additional genetic susceptibility loci for breast cancer, here …

It remains elusive whether some of the associations identified in genome-wide association
studies of prostate cancer (PrCa) may be due to regulatory effects of genetic variants on …

Background Advanced age is associated with cognitive and physical decline and is a major
risk factor for a multitude of disorders. There is also a gap in life expectancy between males …

BACKGROUND Prostate cancer is the most common cancer among men in the UK. Prostate-
specific antigen testing followed by biopsy leads to overdetection, overtreatment as well as …

Objective.-The purpose of the guidelines national committee ccAFU was to propose updated
french guidelines for prostate cancer. Methods.-A Medline search was achieved between …

The promise of drug repurposing is to accelerate the translation of knowledge to treatment of
human disease, bypassing common challenges associated with drug development to be …