Many behavioral and psychological symptoms of dementia (BPSD) share similarities in
executive functioning and communication deficits with those described in several …

Amyotrophic lateral sclerosis (ALS) is a devastating and fatal neurodegenerative disorder,
caused by the degeneration of upper and lower motor neurons for which there is no truly …

Alzheimer's disease (AD) is a neurodegenerative disease mainly associated with aging,
oxidative stress and genetic mutations. There are two pathological proteins involved in AD; …

Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease that affects
selected cortical and spinal neuronal populations, leading to progressive paralysis and …

Histamine is a major peripheral inflammatory mediator and a neurotransmitter in the central
nervous system. We have reported that histamine induces microglia activation and releases …

In this review, we describe the experimental paradigms used in preclinical studies to unravel
the histaminergic brain circuits that modulate the formation and retrieval of memories …

A plethora of genetic and molecular mechanisms have been implicated in the
pathophysiology of the heterogeneous and multifactorial amyotrophic lateral sclerosis (ALS) …

Autism spectrum disorder (ASD) is a heterogenous neurodevelopmental disorder defined by
persistent deficits in social interaction and the presence of patterns of repetitive and …

Recent preclinical and clinical evidence suggest that immune system has a role in the
progression and prognosis of Amyotrophic Lateral Sclerosis (ALS), but the identification of a …

Duration of receptor antagonism, measured as the recovery of agonist responsiveness, is
gaining attention as a method to evaluate the 'effective'target-residence for antagonists …