The β-catenin/TCF-4 pathway regulates the expression of OPN in human osteoarthritic chondrocytes

J Tian, SG Gao, YS Li, C Cheng, ZH Deng… - Journal of Orthopaedic …, 2020 - Springer
Background Cartilage destruction is the main characteristic of osteoarthritis (OA), and
osteopontin (OPN) is elevated in OA articular cartilage; however, the reason for the …

[HTML][HTML] RANKL 介导的诱导破骨细胞分化的相关经典信号通路研究进展

王梦蝶, 吴虹, 王荣慧, 王言, 邓然, 卜妍红, 孙明慧… - 2020 - html.rhhz.net
破骨细胞(osteoclasts, OCs) 源于髓系造血前体细胞, 作为多核细胞参与骨吸收过程. OCs
的过度分化影响骨组织吸收, 常见于骨质疏松症, 类风湿关节炎, 强直性脊柱炎 …

Study of serum and synovial fluid Dickkopf-1 levels in patients with primary osteoarthritis of the knee joint in correlation with disease activity and severity

NH Ibrahim, SM Abdel-Monem… - Egyptian Rheumatology …, 2020 - Springer
Background Osteoarthritis (OA) is a typical complex degenerative articular ailment that
shows focal cartilage loss, new bone formation with involvement of entire joint tissues. Dkk-1 …

[PDF][PDF] Are Markers of High Bone Turnover, Representing Poor Bone Quality, Associated with Pain After Total Knee Arthroplasty?

N LeBlanc, T Grande, V Dasa, L Marrero, J Simkin - medschool.lsuhsc.edu
• Osteoporosis, a disease characterized by decreased bone mass and overall poor bone
quality, is drastically underdiagnosed in patients who undergo total knee arthroplasty (TKA) …

[引用][C] 基于Wnt/β-catenin 信号通路治疗骨关节炎研究热点及应用前景

贝涛, 刘军廷, 黄秋霖, 苏伟, 赵劲民 - 中国组织工程研究, 2020