Restoring synovial homeostasis in rheumatoid arthritis by targeting fibroblast-like synoviocytes
G Nygaard, GS Firestein - Nature Reviews Rheumatology, 2020 - nature.com
Rheumatoid arthritis (RA) is a chronic immune-mediated disease that primarily affects the
synovium of diarthrodial joints. During the course of RA, the synovium transforms into a …
synovium of diarthrodial joints. During the course of RA, the synovium transforms into a …
Epigenetics in rheumatoid arthritis; fibroblast‐like synoviocytes as an emerging paradigm in the pathogenesis of the disease
Rheumatoid arthritis (RA) is characterized by immune dysfunctions and chronic
inflammation that mainly affects diarthrodial joints. Genetics has long been surveyed in …
inflammation that mainly affects diarthrodial joints. Genetics has long been surveyed in …
MicroRNAs in synovial pathology associated with osteoarthritis
G Tavallaee, JS Rockel, S Lively, M Kapoor - Frontiers in medicine, 2020 - frontiersin.org
Osteoarthritis (OA) is the most common type of arthritis, a disease that affects the entire joint.
The relative involvement of each tissue, and their interactions, add to the complexity of OA …
The relative involvement of each tissue, and their interactions, add to the complexity of OA …
miR-431-5p regulates cell proliferation and apoptosis in fibroblast-like synoviocytes in rheumatoid arthritis by targeting XIAP
Y Wang, K Zhang, X Yuan, N Xu, S Zhao, L Hou… - Arthritis Research & …, 2020 - Springer
Abstract Background miR-431-5p is dysregulated in various cancers and plays an important
function in the development of cancer. However, its role in fibroblast-like synoviocytes …
function in the development of cancer. However, its role in fibroblast-like synoviocytes …
MicroRNA-34a Promotes Apoptosis of Rheumatoid Arthritis Fbroblast-Like Synoviocyte via AMPK/Akt/mTOR Signaling Pathway
J Ni, Z Hao - Journal of Biomaterials and Tissue Engineering, 2020 - ingentaconnect.com
Background and Objectives: Rheumatoid arthritis (RA) is an autoimmune arthropathy
characterised by chronic synovitis, joint cartilage breakdown and bone erosions. The life …
characterised by chronic synovitis, joint cartilage breakdown and bone erosions. The life …