The extracellular matrix (ECM) surrounding cells is indispensable for regulating their
behavior. The dynamics of ECM signaling are tightly controlled throughout growth and …

Introduction: Metastatic cancers are extremely difficult to treat, and account for the vast
majority of cancer-related deaths. The dissemination of tumor cells to distant sites is highly …

The mineral dust-induced gene (mdig) is overexpressed in a number of human cancers,
suggesting critical roles of this gene played on the pathogenesis of cancers. Unlike several …

Background Non-small cell lung cancer (NSCLC) is the most common cause of cancer-
death due to early metastatic spread, in many cases primarily to the brain. Organ-specific …

During malignant progression to overt cancer cells, normal cells accumulate multiple genetic
and non‑genetic changes, which result in the acquisition of various oncogenic properties …