Immune signatures measured at baseline and immediately prior to vaccination may predict
the immune response to vaccination. Such pre-vaccine assessment might allow not only …

Infectious diseases are a major cause for morbidity and mortality in the older population.
Demographic changes will lead to increasing numbers of older persons over the next …

At the time of writing this commentary (February 2020), the coronavirus COVID‐19 epidemic
has already resulted in more fatalities compared with the SARS and MERS coronavirus …

Known since Hippocrates and of continuing public health importance, influenza remains a
major cause of morbidity and mortality worldwide, and large segments of the human …

A degraded/dysfunctional immune system appears to be the main determinant of
serious/fatal reaction to viral infection (for COVID-19, SARS, and influenza alike). There are …

Although traditional egg-based inactivated influenza vaccines can protect against infection,
there have been significant efforts to develop improved formats to overcome disadvantages …

Seasonal influenza vaccines prevent influenza-related illnesses, hospitalizations, and
deaths. However, these vaccines are not as effective as other viral vaccines, and there is …

Abstract 2018/19 was the first season of introduction of a newly licensed adjuvanted
influenza vaccine (aTIV) for adults aged 65 years and over and the sixth season in the roll …

Abstract 2013/14 saw the start of the introduction of a new live attenuated influenza vaccine
(LAIV) programme for children in England. 2018/19 saw co-circulation of both A (H1N1) …

Introduction Annual influenza vaccination is recommended for older adults, but evidence
regarding the impact of repeated vaccination has been inconclusive. Aim We investigated …