Role of androgen and microRNA in triple-negative breast cancer

N Al-Othman, M Ahram, M Alqaraleh - Breast disease, 2020 - content.iospress.com
Breast cancer (BC) is the most frequent type of malignancy affecting females worldwide.
Molecular–based studies resulted in an identification of at least four subtypes of breast …

[HTML][HTML] A cancer-specific ubiquitin ligase drives mRNA alternative polyadenylation by ubiquitinating the mRNA 3′ end processing complex

SW Yang, L Li, JP Connelly, SN Porter, K Kodali… - Molecular cell, 2020 - cell.com
Alternative polyadenylation (APA) contributes to transcriptome complexity by generating
mRNA isoforms with varying 3′ UTR lengths. APA leading to 3′ UTR shortening (3′ US) …

[HTML][HTML] MiRNA-671-5p Promotes prostate cancer development and metastasis by targeting NFIA/CRYAB axis

Z Zhu, L Luo, Q Xiang, J Wang, Y Liu, Y Deng… - Cell Death & …, 2020 - nature.com
Prostate cancer (PCa) is the second cause of death due to malignancy among men, and
metastasis is the leading cause of mortality in patients with PCa. MicroRNAs (miRNAs) play …

[HTML][HTML] Fibroblast subtypes define a metastatic matrisome in breast cancer

HM Brechbuhl, AS Barrett, E Kopin, JC Hagen… - JCI insight, 2020 - ncbi.nlm.nih.gov
Small primary breast cancers can show surprisingly high potential for metastasis. Clinical
decision-making for tumor aggressiveness, including molecular profiling, relies primarily on …

miR-423 promotes breast cancer invasion by activating NF-κB signaling

T Dai, X Zhao, Y Li, L Yu, Y Li, X Zhou… - OncoTargets and …, 2020 - Taylor & Francis
Objective Breast cancer has become the most common malignancy among women
worldwide; therefore, novel diagnostic and prognostic markers and therapeutic targets are …

Long non-coding RNA LOC285194 in cancer

L Luo, M Wang, X Li, J Tian, K Zhang, S Tan, C Luo - Clinica Chimica Acta, 2020 - Elsevier
Long non-coding RNAs (lncRNAs) are non-protein-encoding RNAs that are usually over
200 nucleotides-long. The development of whole-genome sequencing has enabled the …

[HTML][HTML] Profiling pro-neural to mesenchymal transition identifies a lncRNA signature in glioma

Q Liang, G Guan, X Li, C Wei, J Wu, P Cheng… - Journal of Translational …, 2020 - Springer
Background Molecular classification has laid the framework for exploring glioma biology and
treatment strategies. Pro-neural to mesenchymal transition (PMT) of glioma is known to be …

Unraveling the role of the RNA-binding protein MUSASHI1 in chemoresistance and malignancy of Glioblastoma

R Pötschke - 2020 - repo.bibliothek.uni-halle.de
The RNA-binding protein (RBP) Musashi (MSI1) is reported to control the mRNA translation
of various target transcripts to promote cell cycle progression. It is highly abundant during …