Role of androgen and microRNA in triple-negative breast cancer
Breast cancer (BC) is the most frequent type of malignancy affecting females worldwide.
Molecular–based studies resulted in an identification of at least four subtypes of breast …
Molecular–based studies resulted in an identification of at least four subtypes of breast …
[HTML][HTML] A cancer-specific ubiquitin ligase drives mRNA alternative polyadenylation by ubiquitinating the mRNA 3′ end processing complex
Alternative polyadenylation (APA) contributes to transcriptome complexity by generating
mRNA isoforms with varying 3′ UTR lengths. APA leading to 3′ UTR shortening (3′ US) …
mRNA isoforms with varying 3′ UTR lengths. APA leading to 3′ UTR shortening (3′ US) …
[HTML][HTML] MiRNA-671-5p Promotes prostate cancer development and metastasis by targeting NFIA/CRYAB axis
Z Zhu, L Luo, Q Xiang, J Wang, Y Liu, Y Deng… - Cell Death & …, 2020 - nature.com
Prostate cancer (PCa) is the second cause of death due to malignancy among men, and
metastasis is the leading cause of mortality in patients with PCa. MicroRNAs (miRNAs) play …
metastasis is the leading cause of mortality in patients with PCa. MicroRNAs (miRNAs) play …
[HTML][HTML] Fibroblast subtypes define a metastatic matrisome in breast cancer
HM Brechbuhl, AS Barrett, E Kopin, JC Hagen… - JCI insight, 2020 - ncbi.nlm.nih.gov
Small primary breast cancers can show surprisingly high potential for metastasis. Clinical
decision-making for tumor aggressiveness, including molecular profiling, relies primarily on …
decision-making for tumor aggressiveness, including molecular profiling, relies primarily on …
miR-423 promotes breast cancer invasion by activating NF-κB signaling
T Dai, X Zhao, Y Li, L Yu, Y Li, X Zhou… - OncoTargets and …, 2020 - Taylor & Francis
Objective Breast cancer has become the most common malignancy among women
worldwide; therefore, novel diagnostic and prognostic markers and therapeutic targets are …
worldwide; therefore, novel diagnostic and prognostic markers and therapeutic targets are …
Long non-coding RNA LOC285194 in cancer
L Luo, M Wang, X Li, J Tian, K Zhang, S Tan, C Luo - Clinica Chimica Acta, 2020 - Elsevier
Long non-coding RNAs (lncRNAs) are non-protein-encoding RNAs that are usually over
200 nucleotides-long. The development of whole-genome sequencing has enabled the …
200 nucleotides-long. The development of whole-genome sequencing has enabled the …
[HTML][HTML] Profiling pro-neural to mesenchymal transition identifies a lncRNA signature in glioma
Q Liang, G Guan, X Li, C Wei, J Wu, P Cheng… - Journal of Translational …, 2020 - Springer
Background Molecular classification has laid the framework for exploring glioma biology and
treatment strategies. Pro-neural to mesenchymal transition (PMT) of glioma is known to be …
treatment strategies. Pro-neural to mesenchymal transition (PMT) of glioma is known to be …
Unraveling the role of the RNA-binding protein MUSASHI1 in chemoresistance and malignancy of Glioblastoma
R Pötschke - 2020 - repo.bibliothek.uni-halle.de
The RNA-binding protein (RBP) Musashi (MSI1) is reported to control the mRNA translation
of various target transcripts to promote cell cycle progression. It is highly abundant during …
of various target transcripts to promote cell cycle progression. It is highly abundant during …