The postictal state—What do we know?
JCM Pottkämper, J Hofmeijer, JA van Waarde… - …, 2020 - Wiley Online Library
This narrative review provides a broad and comprehensive overview of the most important
discoveries on the postictal state over the past decades as well as recent developments …
discoveries on the postictal state over the past decades as well as recent developments …
[HTML][HTML] Frequency and pathophysiology of post-seizure todd's paralysis
SY Xu, ZX Li, XW Wu, L Li, CX Li - Medical science monitor …, 2020 - ncbi.nlm.nih.gov
Todd's paralysis, a neurological abnormality characterized by temporary limb weakness or
hemiplegia, typically occurs following a seizure, without enduring consequences. Since limb …
hemiplegia, typically occurs following a seizure, without enduring consequences. Since limb …
The lncRNA H19 binding to let‐7b promotes hippocampal glial cell activation and epileptic seizures by targeting Stat3 in a rat model of temporal lobe epilepsy
CL Han, YP Liu, CJ Guo, TT Du, Y Jiang… - Cell …, 2020 - Wiley Online Library
Objectives Glial cell activation contributes to the inflammatory response and occurrence of
epilepsy. Our preliminary study demonstrated that the long non‐coding RNA, H19, promotes …
epilepsy. Our preliminary study demonstrated that the long non‐coding RNA, H19, promotes …
[HTML][HTML] Seizures elevate gliovascular unit Ca2+ and cause sustained vasoconstriction
Seizures can result in a severe hypoperfusion/hypoxic attack that causes postictal memory
and behavioral impairments. However, neither postictal changes to microvasculature nor Ca …
and behavioral impairments. However, neither postictal changes to microvasculature nor Ca …
Anandamide signaling augmentation rescues amygdala synaptic function and comorbid emotional alterations in a model of epilepsy
Epilepsy is often associated with emotional disturbances and the endocannabinoid (eCB)
system tunes synaptic transmission in brain regions regulating emotional behavior. Thus …
system tunes synaptic transmission in brain regions regulating emotional behavior. Thus …
Postictal brainstem hypoperfusion and risk factors for sudden unexpected death in epilepsy
Objective Since the strongest risk factor for sudden unexpected death in epilepsy (SUDEP)
is frequent bilateral tonic-clonic seizures (BTCS), our aim was to determine whether postictal …
is frequent bilateral tonic-clonic seizures (BTCS), our aim was to determine whether postictal …
[HTML][HTML] In vivo assessment of mechanisms underlying the neurovascular basis of postictal amnesia
Long-lasting confusion and memory difficulties during the postictal state remain a major
unmet problem in epilepsy that lacks pathophysiological explanation and treatment. We …
unmet problem in epilepsy that lacks pathophysiological explanation and treatment. We …
Aspects of cAMP signaling in epileptogenesis and seizures and its potential as drug target
C Mertz, S Krarup, CD Jensen, SEH Lindholm… - Neurochemical …, 2020 - Springer
Epilepsy is one of the most common chronic neurological conditions. Today, close to 30
different medications to prevent epileptic seizures are in use; yet, far from all patients …
different medications to prevent epileptic seizures are in use; yet, far from all patients …
Dynamic oxygen changes during status epilepticus and subsequent endogenous kindling
MD Wolff, JS Farrell, MH Scantlebury, GC Teskey - Epilepsia, 2020 - Wiley Online Library
Objective Brain tissue oxygen (partial oxygen pressure [pO2]) levels are tightly regulated to
stay within the normoxic zone, with deviations on either side resulting in impaired brain …
stay within the normoxic zone, with deviations on either side resulting in impaired brain …
Seven‐tesla susceptibility‐weighted analysis of hippocampal venous structures: Application to magnetic‐resonance–normal focal epilepsy
RE Feldman, LV Marcuse, G Verma, SSG Brown… - …, 2020 - Wiley Online Library
Objective Vascular structures may play a significant role in epileptic pathology. Although
previous attempts to characterize vasculature relative to epileptogenic zones and …
previous attempts to characterize vasculature relative to epileptogenic zones and …