[HTML][HTML] Natural products and their bioactive compounds: neuroprotective potentials against neurodegenerative diseases

NS Mohd Sairazi, KNS Sirajudeen - … -Based Complementary and …, 2020 - hindawi.com
In recent years, natural products, which originate from plants, animals, and fungi, together
with their bioactive compounds have been intensively explored and studied for their …

Neurotropism of SARS-CoV-2 and its neuropathological alterations: Similarities with other coronaviruses

J Hu, J Jolkkonen, C Zhao - Neuroscience & Biobehavioral Reviews, 2020 - Elsevier
A novel coronavirus (SARS-CoV-2) emerged from Wuhan, China, and spread quickly
around the world. In addition to fever, cough and shortness of breath, it was confirmed that …

Possible routes of SARS‐CoV‐2 invasion in brain: in context of neurological symptoms in COVID‐19 patients

A Kumar, V Pareek, P Prasoon, MA Faiq… - Journal of …, 2020 - Wiley Online Library
Manifestation of neurological symptoms in certain patients of coronavirus disease‐2019
(COVID‐19) has warranted for their virus‐induced etiogenesis. SARS‐CoV‐2, the causative …

Microglia heterogeneity and neurodegeneration: The emerging paradigm of the role of immunity in Alzheimer's disease

A Hashemiaghdam, M Mroczek - Journal of neuroimmunology, 2020 - Elsevier
Alzheimer's disease (AD) is the most common dementia type affecting nearly 44 million
people worldwide. Recent findings point to microglia as a significant contributor to neural …

Inflammatory cytokines associate with neuroimaging after acute mild traumatic brain injury

KA Edwards, CL Pattinson, VA Guedes, J Peyer… - Frontiers in …, 2020 - frontiersin.org
Introduction: Elevated levels of blood-based proinflammatory cytokines are linked to acute
moderate to severe traumatic brain injuries (TBIs), yet less is known in acute mild (m) TBI …

[HTML][HTML] Inflammatory and immune mechanisms underlying epileptogenesis and epilepsy: from pathogenesis to treatment target

I Mukhtar - Seizure, 2020 - Elsevier
Epilepsy is a brain disease associated with epileptic seizures as well as with
neurobehavioral outcomes of this condition. In the last century, inflammation emerged as a …

Rps27a might act as a controller of microglia activation in triggering neurodegenerative diseases

N Khayer, M Mirzaie, SA Marashi, M Jalessi - Plos one, 2020 - journals.plos.org
Neurodegenerative diseases (NDDs) are increasing serious menaces to human health in
the recent years. Despite exhibiting different clinical phenotypes and selective neuronal …

Interleukin 10 restores lipopolysaccharide-induced alterations in synaptic plasticity probed by repetitive magnetic stimulation

M Lenz, A Eichler, P Kruse, A Strehl… - Frontiers in …, 2020 - frontiersin.org
Systemic inflammation is associated with alterations in complex brain functions such as
learning and memory. However, diagnostic approaches to functionally assess and quantify …

[HTML][HTML] Integrated analysis of the proteome and transcriptome in a MCAO mouse model revealed the molecular landscape during stroke progression

L Li, L Dong, Z Xiao, W He, J Zhao, H Pan… - Journal of Advanced …, 2020 - Elsevier
Strokes usually results in long-term disability and death, and they occur worldwide.
Recently, increased research on both on the physiopathological mechanisms and the …

[HTML][HTML] Glycogen Synthase Kinase 3β Promotes Postoperative Cognitive Dysfunction by Inducing the M1 Polarization and Migration of Microglia

J Li, C Shi, Z Ding, W Jin - Mediators of inflammation, 2020 - hindawi.com
Postoperative cognitive dysfunction (POCD) is a common postoperative central nervous
system complication, especially in the elderly. It has been consistently reported that the …