Design, synthesis, and evaluation of new 2-(quinoline-4-yloxy) acetamide-based antituberculosis agents

AF Borsoi, JD Paz, BL Abbadi, FS Macchi… - European Journal of …, 2020 - Elsevier
Using a classical molecular simplification approach, a series of 36 quinolines were
synthesized and evaluated as in vitro inhibitors of Mycobacterium tuberculosis (M …

[HTML][HTML] Using Bayesian spatial models to map and to identify geographical hotspots of multidrug-resistant tuberculosis in Portugal between 2000 and 2016

O Oliveira, AI Ribeiro, ET Krainski, T Rito, R Duarte… - Scientific reports, 2020 - nature.com
Multidrug-resistant tuberculosis (MDR-TB) is a major threat to the eradication of tuberculosis.
TB control strategies need to be adapted to the necessities of different countries and …

[HTML][HTML] Using genomics to understand the origin and dispersion of multidrug and extensively drug resistant tuberculosis in Portugal

J Perdigão, P Gomes, A Miranda, F Maltez… - Scientific reports, 2020 - nature.com
Portugal is a low incidence country for tuberculosis (TB) disease. Now figuring among TB
low incidence countries, it has since the 1990s reported multidrug resistant and extensively …

Emergence of multidrug-resistant Mycobacterium tuberculosis of the Beijing lineage in Portugal and Guinea-Bissau: a snapshot of moving clones by whole-genome …

J Perdigão, C Silva, F Maltez, D Machado… - Emerging microbes & …, 2020 - Taylor & Francis
The Beijing genotype comprises a highly disseminated strain type that is frequently
associated with multidrug resistant (MDR) tuberculosis (TB) and increased transmissibility …

[图书][B] Whole genome sequencing for epidemiological studies of tuberculosis: a systematic review of reporting practices and factors associated with reporting quality of …

B Cheng - 2020 - search.proquest.com
Background: Whole-genome sequencing (WGS) has the potential to improve the
understanding of tuberculosis (TB) epidemiology. However, standardized reporting is …

[引用][C] http://eprints. gla. ac. uk/210147