Propulsive nanomachines: the convergent evolution of archaella, flagella and cilia

M Beeby, JL Ferreira, P Tripp, SV Albers… - FEMS microbiology …, 2020 - academic.oup.com
Echoing the repeated convergent evolution of flight and vision in large eukaryotes,
propulsive swimming motility has evolved independently in microbes in each of the three …

Protein supramolecular structures: from self-assembly to nanovaccine design

X Zottig, M Côté-Cyr, D Arpin, D Archambault… - Nanomaterials, 2020 - mdpi.com
Life-inspired protein supramolecular assemblies have recently attracted considerable
attention for the development of next-generation vaccines to fight against infectious …

Membrane constriction and thinning by sequential ESCRT-III polymerization

HC Nguyen, N Talledge, J McCullough, A Sharma… - Biophysical …, 2020 - cell.com
The Endosomal Sorting Complexes Required for Transport (ESCRTs) mediate diverse
membrane remodeling events. These activities typically require ESCRT-III proteins to …

Shape-shifting peptide nanomaterials: surface asymmetry enables pH-dependent formation and interconversion of collagen tubes and sheets

AD Merg, G Touponse, E Genderen… - Journal of the …, 2020 - ACS Publications
The fabrication of dynamic, transformable biomaterials that respond to environmental cues
represents a significant step forward in the development of synthetic materials that rival their …

Campylobacter jejuni motility integrates specialized cell shape, flagellar filament, and motor, to coordinate action of its opposed flagella

EJ Cohen, D Nakane, Y Kabata, DR Hendrixson… - PLoS …, 2020 - journals.plos.org
Campylobacter jejuni rotates a flagellum at each pole to swim through the viscous mucosa
of its hosts' gastrointestinal tracts. Despite their importance for host colonization, however …

Structural conservation and adaptation of the bacterial flagella motor

BL Carroll, J Liu - Biomolecules, 2020 - mdpi.com
Many bacteria require flagella for the ability to move, survive, and cause infection. The
flagellum is a complex nanomachine that has evolved to increase the fitness of each …

Atomic structure of the Campylobacter jejuni flagellar filament reveals how ε Proteobacteria escaped Toll-like receptor 5 surveillance

MAB Kreutzberger, C Ewing, F Poly… - Proceedings of the …, 2020 - National Acad Sciences
Vertebrates, from zebra fish to humans, have an innate immune recognition of many
bacterial flagellins. This involves a conserved eight-amino acid epitope in flagellin …

An asymmetric sheath controls flagellar supercoiling and motility in the leptospira spirochete

KH Gibson, F Trajtenberg, EA Wunder, MR Brady… - Elife, 2020 - elifesciences.org
Spirochete bacteria, including important pathogens, exhibit a distinctive means of swimming
via undulations of the entire cell. Motility is powered by the rotation of supercoiled' …

Prototypic SNARE proteins are encoded in the genomes of Heimdallarchaeota, potentially bridging the gap between the prokaryotes and eukaryotes

E Neveu, D Khalifeh, N Salamin, D Fasshauer - Current Biology, 2020 - cell.com
A defining feature of eukaryotic cells is the presence of numerous membrane-bound
organelles that subdivide the intracellular space into distinct compartments. How the …

The cryo-EM structure of the bacterial flagellum cap complex suggests a molecular mechanism for filament elongation

NS Al-Otaibi, AJ Taylor, DP Farrell, SB Tzokov… - Nature …, 2020 - nature.com
The bacterial flagellum is a remarkable molecular motor, whose primary function in bacteria
is to facilitate motility through the rotation of a filament protruding from the bacterial cell. A …