The molecular and functional characteristics of HLA-G and the interaction with its receptors: where to intervene for cancer immunotherapy?

JVD Attia, CE Dessens, R van de Water… - International journal of …, 2020 - mdpi.com
Human leukocyte antigen G (HLA-G) mediates maternal-fetal immune tolerance. It is also
considered an immune checkpoint in cancer since it may mediate immune evasion and thus …

Generation of hypoimmunogenic human pluripotent stem cells via expression of membrane-bound and secreted β2m-HLA-G fusion proteins

L Shi, W Li, Y Liu, Z Chen, Y Hui, P Hao, X Xu… - Stem Cells, 2020 - academic.oup.com
Allogeneic immune rejection is a major barrier for the application of human pluripotent stem
cells (hPSCs) in regenerative medicine. A broad spectrum of immune cells, including T cells …

HLA‐G: Function, polymorphisms and pathology

HLA-G immune modulatory genes and molecules are presently being studied by a
widespread number of research groups. In the present study, we do not aim to be exhaustive …