Neurotoxicity of e-cigarettes

JA Ruszkiewicz, Z Zhang, FM Gonçalves… - Food and Chemical …, 2020 - Elsevier
It appears that electronic cigarettes (EC) are a less harmful alternative to conventional
cigarette (CC) smoking, as they generate substantially lower levels of harmful carcinogens …

Vaping in adolescents: epidemiology and respiratory harm

ES Hamberger, B Halpern-Felsher - Current opinion in pediatrics, 2020 - journals.lww.com
Although the long-term harms of regular e-cigarette use are unknown, numerous studies
including early longitudinal data suggest e-cigarette use is associated with incidence of …

Chemical adducts of reactive flavor aldehydes formed in e-cigarette liquids are cytotoxic and inhibit mitochondrial function in respiratory epithelial cells

SV Jabba, AN Diaz, HC Erythropel… - Nicotine and …, 2020 - academic.oup.com
Introduction Flavor aldehydes in e-cigarettes, including vanillin, ethyl vanillin (vanilla), and
benzaldehyde (berry/fruit), rapidly undergo chemical reactions with the e-liquid solvents …

E-cigarette constituents propylene glycol and vegetable glycerin decrease glucose uptake and its metabolism in airway epithelial cells in vitro

M Woodall, J Jacob, KK Kalsi… - … of Physiology-Lung …, 2020 - journals.physiology.org
Electronic nicotine delivery systems, or e-cigarettes, utilize a liquid solution that normally
contains propylene glycol (PG) and vegetable glycerin (VG) to generate vapor and act as a …

[HTML][HTML] Sub-ohm vaping increases the levels of carbonyls, is cytotoxic, and alters gene expression in human bronchial epithelial cells exposed at the air–liquid …

A Noël, E Hossain, Z Perveen, H Zaman, AL Penn - Respiratory research, 2020 - Springer
Background Exposure to electronic-cigarette (e-cig) aerosols induces potentially fatal e-cig
or vaping-associated lung injury (EVALI). The cellular and molecular mechanisms …

Electronic cigarette refill fluids sold worldwide: flavor chemical composition, toxicity, and hazard analysis

EE Omaiye, W Luo, KJ McWhirter… - Chemical research in …, 2020 - ACS Publications
Flavor chemicals in electronic cigarette (EC) fluids, which may negatively impact human
health, have been studied in a limited number of countries/locations. To gain an …

The JUUL e-cigarette elevates the risk of thrombosis and potentiates platelet activation

JEM Ramirez, ZA Karim, AB Alarabi… - Journal of …, 2020 - journals.sagepub.com
Background: Smoking is the main preventable cause of death in the United States and
worldwide and is associated with serious cardiovascular health consequences, including …

Electronic nicotine delivery system aerosol-induced cell death and dysfunction in macrophages and lung epithelial cells

GL Serpa, ND Renton, N Lee, MJ Crane… - American journal of …, 2020 - atsjournals.org
Electronic nicotine delivery system (ENDS) use is outpacing our understanding of its
potential harmful effects. Homeostasis of the lung is maintained through proper balance of …

[HTML][HTML] E-liquid containing a mixture of coconut, vanilla, and cookie flavors causes cellular senescence and dysregulated repair in pulmonary fibroblasts: implications …

JH Lucas, T Muthumalage, Q Wang… - Frontiers in …, 2020 - frontiersin.org
Electronic cigarette (e-cig) usage has risen dramatically worldwide over the past decade.
While they are touted as a safe alternative to cigarettes, recent studies indicate that high …

Flavored e-liquids increase cytoplasmic Ca2+ levels in airway epithelia

TR Rowell, JE Keating, BT Zorn… - … of Physiology-Lung …, 2020 - journals.physiology.org
E-cigarettes are noncombustible, electronic nicotine-delivery devices that aerosolize an e-
liquid, ie, nicotine, in a propylene glycol-vegetable glycerin vehicle that also contains flavors …