A critical review of bottom-up proteomics: the good, the bad, and the future of this field
EJ Dupree, M Jayathirtha, H Yorkey, M Mihasan… - Proteomes, 2020 - mdpi.com
Proteomics is the field of study that includes the analysis of proteins, from either a basic
science prospective or a clinical one. Proteins can be investigated for their abundance …
science prospective or a clinical one. Proteins can be investigated for their abundance …
Recent advancements in polyethyleneimine-based materials and their biomedical, biotechnology, and biomaterial applications
Cationic polymers, known for their highly positive charges, have historically dominated the
materials used in bioengineering. However, the demand for intelligent systems with high …
materials used in bioengineering. However, the demand for intelligent systems with high …
Ultra-high-throughput clinical proteomics reveals classifiers of COVID-19 infection
The COVID-19 pandemic is an unprecedented global challenge, and point-of-care
diagnostic classifiers are urgently required. Here, we present a platform for ultra-high …
diagnostic classifiers are urgently required. Here, we present a platform for ultra-high …
Rapid, deep and precise profiling of the plasma proteome with multi-nanoparticle protein corona
JE Blume, WC Manning, G Troiano, D Hornburg… - Nature …, 2020 - nature.com
Large-scale, unbiased proteomics studies are constrained by the complexity of the plasma
proteome. Here we report a highly parallel protein quantitation platform integrating …
proteome. Here we report a highly parallel protein quantitation platform integrating …
Facile synthesis of novel reduced graphene oxide@ polystyrene nanospheres for sensitive label-free electrochemical immunoassay
Q Lan, H Shen, J Li, C Ren, X Hu, Z Yang - Chemical Communications, 2020 - pubs.rsc.org
Herein, we report the synthesis of novel nanosized reduced graphene oxide@ polystyrene
nanospheres (rGO@ PS NSs) through an electrostatic interaction method, and further their …
nanospheres (rGO@ PS NSs) through an electrostatic interaction method, and further their …
Conjugating immunoassays to mass spectrometry: Solutions to contemporary challenges in clinical diagnostics
KG Stevens, TL Pukala - TrAC Trends in Analytical Chemistry, 2020 - Elsevier
Developments in immunoassays and mass spectrometry have independently influenced
diagnostic technology. However, both techniques possess unique strengths and limitations …
diagnostic technology. However, both techniques possess unique strengths and limitations …
Rapid prostate cancer noninvasive biomarker screening using segmented flow mass spectrometry-based untargeted metabolomics
Spectrometric methods with rapid biomarker detection capacity through untargeted
metabolomics are becoming essential in the clinical cancer research. Liquid …
metabolomics are becoming essential in the clinical cancer research. Liquid …
Analytical chemistry in the 21st century: Challenges, solutions, and future perspectives of complex matrices quantitative analyses in biological/clinical field
Nowadays, the challenges in analytical chemistry, and mostly in quantitative analysis,
include the development and validation of new materials, strategies and procedures to meet …
include the development and validation of new materials, strategies and procedures to meet …
Microwave-assisted preparation of ZnFe2O4-Ag/rGO nanocomposites for amplification signal detection of alpha-fetoprotein
M Wu, Y Yang, K Cao, C Zhao, X Qiao, C Hong - Bioelectrochemistry, 2020 - Elsevier
In this study, a novel signal-amplified immunosensor was designed by using a microwave-
assisted self-assembly method to synthesize ZnFe 2 O 4-Ag/rGO nanocomposites. The …
assisted self-assembly method to synthesize ZnFe 2 O 4-Ag/rGO nanocomposites. The …
Clinical classifiers of COVID-19 infection from novel ultra-high-throughput proteomics
CB Messner, V Demichev, D Wendisch, L Michalick… - MedRxiv, 2020 - medrxiv.org
The COVID-19 pandemic is an unprecedented global challenge. Highly variable in its
presentation, spread and clinical outcome, novel point-of-care diagnostic classifiers are …
presentation, spread and clinical outcome, novel point-of-care diagnostic classifiers are …