Proteins carry out a wide variety of catalytic, regulatory, signalling and structural functions in
living systems. Following their assembly on ribosomes and throughout their lifetimes, most …

Tick saliva contains a complex mixture of peptides and non-peptides that counteract their
hosts' hemostasis, immunity, and tissue-repair reactions. Recent transcriptomic studies have …

Although the majority of proteins used for biomedical research are produced using living
systems such as bacteria, biological means for producing proteins can be advantageously …

The decoration of proteins with post-translational modifications (PTMs) serves as a
mechanism to expand the functional repertoire of the proteome. Tyrosine sulfation is a PTM …

Targeting chemokine signaling is an attractive avenue for the treatment of inflammatory
disorders. Tyrosine sulfation is an important post-translational modification (PTM) that …

The haemathrins are tick-derived thrombin-inhibiting proteins predicted to be post-
translationally sulfated. This study reports the ligation-based assembly of eight …

α-Conotoxins (Ctx) can selectively target distinct subtypes of nicotinic acetylcholine
receptors (nAChRs), which are closely related to a number of neurological diseases, and …