Neuropsychopathology of autism spectrum disorder: complex interplay of genetic, epigenetic, and environmental factors
R Bhandari, JK Paliwal, A Kuhad - … food intervention and therapy for autism …, 2020 - Springer
Autism spectrum disorder (ASD) is a complex heterogeneous consortium of pervasive
development disorders (PDD) which ranges from atypical autism, autism, and Asperger …
development disorders (PDD) which ranges from atypical autism, autism, and Asperger …
[HTML][HTML] Rat models of human diseases and related phenotypes: a systematic inventory of the causative genes
C Szpirer - Journal of biomedical science, 2020 - Springer
The laboratory rat has been used for a long time as the model of choice in several
biomedical disciplines. Numerous inbred strains have been isolated, displaying a wide …
biomedical disciplines. Numerous inbred strains have been isolated, displaying a wide …
[HTML][HTML] Distinct dynamics of social motivation drive differential social behavior in laboratory rat and mouse strains
S Netser, A Meyer, H Magalnik, A Zylbertal… - Nature …, 2020 - nature.com
Mice and rats are widely used to explore mechanisms of mammalian social behavior in
health and disease, raising the question whether they actually differ in their social behavior …
health and disease, raising the question whether they actually differ in their social behavior …
[HTML][HTML] Distinct mechanisms of over-representation of landmarks and rewards in the hippocampus
M Sato, K Mizuta, T Islam, M Kawano, Y Sekine… - Cell reports, 2020 - cell.com
In the hippocampus, locations associated with salient features are represented by a
disproportionately large number of neurons, but the cellular and molecular mechanisms …
disproportionately large number of neurons, but the cellular and molecular mechanisms …
[HTML][HTML] Experimental models to study autism spectrum disorders: hiPSCs, rodents and zebrafish
Autism Spectrum Disorders (ASD) affect around 1.5% of the global population, which
manifest alterations in communication and socialization, as well as repetitive behaviors or …
manifest alterations in communication and socialization, as well as repetitive behaviors or …
[HTML][HTML] Proteomic analysis of brain region and sex-specific synaptic protein expression in the adult mouse brain
U Distler, S Schumann, HG Kesseler, R Pielot… - Cells, 2020 - mdpi.com
Genetic disruption of synaptic proteins results in a whole variety of human neuropsychiatric
disorders including intellectual disability, schizophrenia or autism spectrum disorder (ASD) …
disorders including intellectual disability, schizophrenia or autism spectrum disorder (ASD) …
Spontaneous social communication in laboratory mice-placing ultrasonic vocalizations in their behavioral context
E Ey, F de Chaumont, T Bourgeron - bioRxiv, 2020 - biorxiv.org
In their natural habitat, mice interact and communicate to regulate major functions, such as
reproduction, group coordination, and protection. Nevertheless, little is currently known …
reproduction, group coordination, and protection. Nevertheless, little is currently known …
[PDF][PDF] 孤独症谱系障碍实验动物模型研究进展
李燊， 吴海涛 - 中国药理学与毒理学杂志, 2020 - cjpt.magtechjournal.com
孤独症谱系障碍(ASD) 的发生是遗传和环境相互作用的结果. 建立不同因素诱发的ASD
动物模型, 并探讨其行为学, 神经环路与分子信号机制, 对于揭示ASD 的发生机制 …
动物模型, 并探讨其行为学, 神经环路与分子信号机制, 对于揭示ASD 的发生机制 …