Pyroptosis, a form of programmed cell death, has garnered increasing attention as it relates
to innate immunity and diseases. The discovery of caspase-1/3/4/5/8/11 function in sensing …

The voltage-dependent anion channel 1 (VDAC1) protein, is an important regulator of
mitochondrial function, and serves as a mitochondrial gatekeeper, with responsibility for …

Ferroptosis is a novel form of non-apoptotic regulated cell death (RCD), with distinct
characteristics and functions in physical conditions and multiple diseases such as cancers …

Necroptosis, known as programmed necrosis, is a form of caspase-independent, finely
regulated cell death with necrotic morphology. Tumor necrosis, foci of necrotic cell death …

Apoptosis is a universal and continuous event during tissue development, restoration,
repair, and regeneration. Mounting evidence has demonstrated that apoptosis is essential …

The cellular mechanisms underlying hereditary photoreceptor degeneration are still poorly
understood, a problem that is exacerbated by the enormous genetic heterogeneity of this …

C-type lectin-like receptors (CLRs) represent a family of transmembrane pattern recognition
receptors, expressed primarily by myeloid cells. They recognize not only pathogen moieties …

Pyroptosis is a newly discovered untypical form of programmed cell death by inflammatory
response, which is dependent on the classic pathway of Caspase-1 and the non-canonical …

Based on high quality surgery and scientific data, scientists and surgeons are committed to
protecting patients as well as healthcare staff and hereby provide this Guidance to address …

The adult heart is a post-mitotic terminally differentiated organ; therefore, beyond
development, cardiomyocyte cell death is maladaptive. Heart disease is the leading cause …