Interactions of the choroid, Bruch's membrane, retinal pigment epithelium, and neurosensory retina collaborate to form the outer blood-retinal-barrier
MA Fields, LV Del Priore, RA Adelman… - Progress in retinal and …, 2020 - Elsevier
The three interacting components of the outer blood-retinal barrier are the retinal pigment
epithelium (RPE), choriocapillaris, and Bruch's membrane, the extracellular matrix that lies …
epithelium (RPE), choriocapillaris, and Bruch's membrane, the extracellular matrix that lies …
A glance on the role of actin in osteogenic and adipogenic differentiation of mesenchymal stem cells
AU Khan, R Qu, T Fan, J Ouyang, J Dai - Stem cell research & therapy, 2020 - Springer
Mesenchymal stem cells (MSCs) have the capacity to differentiate into multiple lineages
including osteogenic and adipogenic lineages. An increasing number of studies have …
including osteogenic and adipogenic lineages. An increasing number of studies have …
Biomechanical regulation of focal adhesion and invadopodia formation
OY Revach, I Grosheva, B Geiger - Journal of cell science, 2020 - journals.biologists.com
Integrin adhesions are a structurally and functionally diverse family of transmembrane, multi-
protein complexes that link the intracellular cytoskeleton to the extracellular matrix (ECM) …
protein complexes that link the intracellular cytoskeleton to the extracellular matrix (ECM) …
Polymer hydrogels to guide organotypic and organoid cultures
V Magno, A Meinhardt, C Werner - Advanced Functional …, 2020 - Wiley Online Library
Human organotypic and organoid cultures provide increasingly life‐like models of
tissue/organ development and disease, enable more realistic drug screening, and may …
tissue/organ development and disease, enable more realistic drug screening, and may …
Biomimetic networks with enhanced photodynamic antimicrobial activity from conjugated polythiophene/polyisocyanide hybrid hydrogels
Hybrid biomimetic hydrogels with enhanced reactive oxygen species (ROS)‐generation
efficiency under 600 nm light show high antibacterial activity. The hybrid gels are composed …
efficiency under 600 nm light show high antibacterial activity. The hybrid gels are composed …
Osteocyte-mediated translation of mechanical stimuli to cellular signaling and its role in bone and non-bone-related clinical complications
Y Yan, L Wang, L Ge, JL Pathak - Current osteoporosis reports, 2020 - Springer
Abstract Purpose of Review Osteocytes comprise> 95% of the cellular component in bone
tissue and produce a wide range of cytokines and cellular signaling molecules in response …
tissue and produce a wide range of cytokines and cellular signaling molecules in response …
Quantifying tensile forces at cell–cell junctions with a DNA-based fluorescent probe
Cells are physically contacting with each other. Direct and precise quantification of forces at
cell–cell junctions is still challenging. Herein, we have developed a DNA-based ratiometric …
cell–cell junctions is still challenging. Herein, we have developed a DNA-based ratiometric …
Mechanophysical cues in extracellular matrix regulation of cell behavior
T Wang, SS Nanda, GC Papaefthymiou… - ChemBioChem, 2020 - Wiley Online Library
The extracellular matrix (ECM) is a macromolecular network that can provide biochemical
and structural support for cell adhesion and formation. It regulates cell behavior by …
and structural support for cell adhesion and formation. It regulates cell behavior by …
Shear stress modulates osteoblast cell and nucleus morphology and volume
J Jin, RT Jaspers, G Wu, JAM Korfage… - International journal of …, 2020 - mdpi.com
Mechanical loading preserves bone mass and function—yet, little is known about the cell
biological basis behind this preservation. For example, cell and nucleus morphology are …
biological basis behind this preservation. For example, cell and nucleus morphology are …
Microfluidics for the study of mechanotransduction
Mechanical forces regulate a diverse set of biological processes at cellular, tissue, and
organismal length scales. Investigating the cellular and molecular mechanisms that underlie …
organismal length scales. Investigating the cellular and molecular mechanisms that underlie …