[HTML][HTML] The use of immune checkpoint inhibitors in oncology and the occurrence of AKI: where do we stand?

R Franzin, GS Netti, F Spadaccino, C Porta… - Frontiers in …, 2020 - frontiersin.org
Immune checkpoint inhibitors (ICIs) are a novel class of immunotherapy drugs that have
improved the treatment of a broad spectrum of cancers as metastatic melanoma, non-small …

[HTML][HTML] Immune checkpoint inhibitors and immune-related adverse renal events

SM Herrmann, MA Perazella - Kidney international reports, 2020 - Elsevier
Renal toxicities have been increasingly recognized as complications of the immune
checkpoint inhibitors (ICIs). Recent studies have outlined the incidence and potential risk …

[HTML][HTML] Acute kidney injury associated with immune checkpoint inhibitor therapy: incidence, risk factors and outcomes

A Meraz-Muñoz, E Amir, P Ng… - … for immunotherapy of …, 2020 - ncbi.nlm.nih.gov
Background Immune checkpoint inhibitors (ICPi) are a novel and promising anti-cancer
therapy. There are limited data on the incidence, risk factors and outcomes of acute kidney …

[HTML][HTML] Incidence and clinical features of immune-related acute kidney injury in patients receiving programmed cell death ligand-1 inhibitors

H Seethapathy, S Zhao, IA Strohbehn, M Lee… - Kidney international …, 2020 - Elsevier
Background Programmed cell death receptor ligand 1 (PD-L1) inhibitors are immune
checkpoint inhibitors (ICIs) with a side effect profile that may differ from other classes of ICIs …

[HTML][HTML] Nephrotoxicity associated with novel anticancer agents (aflibercept, dasatinib, nivolumab): case series and nephrological considerations

L Piscitani, V Sirolli, L Di Liberato, M Morroni… - International Journal of …, 2020 - mdpi.com
Cancer patients have an incidence of about 60% kidney disease development and are at
elevated risk of acute renal damage. Kidney disease in these patients is frequently …

[HTML][HTML] Renal tubular acidosis and immune checkpoint inhibitor therapy: an immune-related adverse event of PD-1 inhibitor—a report of 3 cases

SM Herrmann, MP Alexander, MF Romero, L Zand - Kidney Medicine, 2020 - Elsevier
The main cause of acute kidney injury in patients receiving immune checkpoint inhibitors
(ICIs) is acute interstitial nephritis. However, as their use continues to increase, other kidney …

Balancing cancer immunotherapy efficacy and toxicity

DB Johnson, BD Jakubovic, V Sibaud… - The Journal of Allergy and …, 2020 - Elsevier
Anti–programmed cell death-1 receptor/programmed cell death-1 receptor ligand–directed
therapies are transforming cancer care, with durable antitumor responses observed in …

[HTML][HTML] Acute interstitial nephritis, a potential predictor of response to immune checkpoint inhibitors in renal cell carcinoma

V Patel, R Elias, J Formella… - … for immunotherapy of …, 2020 - ncbi.nlm.nih.gov
Immune checkpoint inhibitors (ICIs) such as nivolumab and ipilimumab have improved
outcomes in metastatic renal cell carcinoma (mRCC) patients, but they are also associated …

[HTML][HTML] Immune-related adverse events: a retrospective look into the future of oncology in the intensive care unit

A Joseph, A Simonaggio, A Stoclin… - Annals of Intensive …, 2020 - Springer
Background Immune checkpoint inhibitors have reshaped the standard of care in oncology.
However, they have been associated with potentially life-threatening immune-related …

Hyponatremia in the cancer patient

BT Workeneh, KD Jhaveri, H Rondon-Berrios - Kidney international, 2020 - Elsevier
Hyponatremia is a common electrolyte disorder observed in a wide variety of malignancies
and is associated with substantial morbidity and mortality. Newer cancer therapies have …