Gut microbiome and its role in obesity and insulin resistance

CJ Lee, CL Sears, N Maruthur - … of the New York Academy of …, 2020 - Wiley Online Library
Obesity is a complex metabolic disease caused, in part, by the interaction between an
individual's genetics, metabolism, and environment. Emerging evidence supports the role of …

Short chain fatty acids in human gut and metabolic health

EE Blaak, EE Canfora, S Theis, G Frost… - Beneficial …, 2020 - wageningenacademic.com
Evidence is accumulating that short chain fatty acids (SCFA) play an important role in the
maintenance of gut and metabolic health. The SCFA acetate, propionate and butyrate are …

Donor metabolic characteristics drive effects of faecal microbiota transplantation on recipient insulin sensitivity, energy expenditure and intestinal transit time

P de Groot, T Scheithauer, GJ Bakker, A Prodan… - Gut, 2020 - gut.bmj.com
Objective Bariatric surgery improves glucose metabolism. Recent data suggest that faecal
microbiota transplantation (FMT) using faeces from postbariatric surgery diet-induced obese …

[HTML][HTML] Extrinsic factors influencing gut microbes, the immediate consequences and restoring eubiosis

O Bajinka, Y Tan, KA Abdelhalim, G Özdemir, X Qiu - Amb Express, 2020 - Springer
From the emerging studies, the more diverse the microbial population in the gut, the
healthier the gut. Health benefits are associated with the functional characteristics of these …

Effects of underfeeding and oral vancomycin on gut microbiome and nutrient absorption in humans

A Basolo, M Hohenadel, QY Ang, P Piaggi, S Heinitz… - Nature medicine, 2020 - nature.com
Direct evidence in humans for the impact of the microbiome on nutrient absorption is lacking.
We conducted an extended inpatient study using two interventions that we hypothesized …

Impact of calorie restriction on energy metabolism in humans

J Most, LM Redman - Experimental gerontology, 2020 - Elsevier
Calorie restriction (CR) is the most potent, non-pharmacological intervention to support
metabolic health. The effects of calorie restriction exceed weight loss. Consistent throughout …

The composition and richness of the gut microbiota differentiate the top Polish endurance athletes from sedentary controls

M Kulecka, B Fraczek, M Mikula, N Zeber-Lubecka… - Gut …, 2020 - Taylor & Francis
Background Little data are available on the subject of gut microbiota composition in
endurance athletes as well as connections between diet and specific bacteria abundance …

Highly branched RG-I domain enrichment is indispensable for pectin mitigating against high-fat diet-induced obesity

K Zhu, G Mao, D Wu, C Yu, H Cheng… - Journal of Agricultural …, 2020 - ACS Publications
Obesity is associated with gut microbiome dysbiosis. Our previous research has shown that
highly branched rhamnogalacturonan type I (RG-I)-enriched pectin (WRP, 531.5 kDa …

[HTML][HTML] Cross-omics analysis revealed gut microbiome-related metabolic pathways underlying atherosclerosis development after antibiotics treatment

BA Kappel, L De Angelis, M Heiser, M Ballanti… - Molecular …, 2020 - Elsevier
Objective The metabolic influence of gut microbiota plays a pivotal role in the pathogenesis
of cardiometabolic diseases. Antibiotics affect intestinal bacterial diversity, and long-term …

[HTML][HTML] “Western diet”-induced adipose inflammation requires a complex gut microbiota

HQ Tran, A Bretin, A Adeshirlarijaney… - Cellular and Molecular …, 2020 - Elsevier
Background & Aims Consumption of a low-fiber, high-fat, Western-style diet (WSD) induces
adiposity and adipose inflammation characterized by increases in the M1: M2 macrophage …