Recent insights on modulation of inflammasomes by adipokines: a critical event for the pathogenesis of obesity and metabolism-associated diseases
DV Pham, PH Park - Archives of pharmacal research, 2020 - Springer
Aberrant production of adipokines, a group of adipocytes-derived hormones, is considered
one of the most important pathological characteristics of obesity. In individuals with obesity …
one of the most important pathological characteristics of obesity. In individuals with obesity …
Apelin/APJ system: a novel promising target for neurodegenerative diseases
H Luo, L Han, J Xu - Journal of cellular physiology, 2020 - Wiley Online Library
Neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD),
and Huntington's disease (HD), are incurable diseases characterized by progressive loss of …
and Huntington's disease (HD), are incurable diseases characterized by progressive loss of …
Improved neuroprotective effects of gallic acid-loaded chitosan nanoparticles against ischemic stroke
Y Zhao, D Li, Z Zhu, Y Sun - Rejuvenation research, 2020 - liebertpub.com
Ischemic stroke is a typical cerebrovascular illness with high morbidity and mortality
worldwide. Nevertheless, strategies for the prevention and treatment of cerebral …
worldwide. Nevertheless, strategies for the prevention and treatment of cerebral …
Apelin-36 mediates neuroprotective effects by regulating oxidative stress, autophagy and apoptosis in MPTP-induced Parkinson's disease model mice
J Zhu, W Gao, X Shan, C Wang, H Wang, Z Shao… - Brain research, 2020 - Elsevier
Abstract Parkinson's disease (PD), a common human neurodegenerative disorder, is
characterized by the presence of intraneuronal Lewy bodies composed principally of …
characterized by the presence of intraneuronal Lewy bodies composed principally of …
Apelin-13 protects dopaminergic neurons against rotenone—induced neurotoxicity through the AMPK/mTOR/ULK-1 mediated autophagy activation
P Chen, Y Wang, L Chen, N Song, J Xie - International Journal of …, 2020 - mdpi.com
Parkinson's disease (PD) is characterized by the progressive loss of dopaminergic neurons
in the substantia nigra pars compacta. Several brain–gut peptides are able to exert …
in the substantia nigra pars compacta. Several brain–gut peptides are able to exert …
Apelin protects auditory cells from cisplatin-induced toxicity in vitro by inhibiting ROS and apoptosis
H Yin, H Zhang, Y Kong, C Wang, Y Guo, Y Gao… - Neuroscience …, 2020 - Elsevier
Apelin, a specific endogenous ligand of the G protein-coupled receptor APJ, suppresses
oxidative stress and apoptosis in vitro and in vivo. The current study explored whether …
oxidative stress and apoptosis in vitro and in vivo. The current study explored whether …