[HTML][HTML] Molecular mechanisms underlying muscle wasting in Huntington's disease

M Bozzi, F Sciandra - International journal of molecular sciences, 2020 - mdpi.com
Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder caused by
pathogenic expansions of the triplet cytosine-adenosine-guanosine (CAG) within the …

Colorimetric determination of cysteamine based on the aggregation of polyvinylpyrrolidone-stabilized silver nanoparticles

K Shanmugaraj, T Sasikumar, CH Campos… - … Acta Part A: Molecular …, 2020 - Elsevier
A simple, colorimetric and visual method is described for the determination of cysteamine
(CA) using polyvinylpyrrolidone-stabilized silver nanoparticles (PVP-AgNPs) as a …

A simple assay for direct visual and colorimetric sensing application of cysteamine using Au@ Ag core-shell nanoparticles

T Sasikumar, M Ilanchelian - Optical Materials, 2020 - Elsevier
The present study elucidates the preparation of colorimetric Au@ Ag core-shell
nanoparticles (Au@ Ag core-shell NPs) probe for sensitive, label-free and rapid sensing of …

[HTML][HTML] Striatal network modeling in Huntington's Disease

A Ponzi, SJ Barton, KD Bunner… - PLoS computational …, 2020 - journals.plos.org
Medium spiny neurons (MSNs) comprise over 90% of cells in the striatum. In vivo MSNs
display coherent burst firing cell assembly activity patterns, even though isolated MSNs do …

[图书][B] Contributions of the Thalamus to Striatal Pathology and Motor Dysfunction in Huntington's Disease

G Crevier-Sorbo - 2020 - search.proquest.com
Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder
characterized by progressive loss of striatal medium spiny projection neurons (MSN), some …

Variant RNAi

LM Stanek, A Palermo, B Richards, SP Sardi… - US Patent …, 2020 - Google Patents
Provided herein are RNAi molecules including a first strand containing a guide sequence
and a second strand comprising a non-guide sequence where the non-guide sequence …