Aims To assess the effectiveness of brief interventions in primary care aimed at reducing or
discontinuing long‐term benzodiazepine/Z‐drug (BZRA) use. Method Systematic review of …

Recent studies have revealed a growing number of patients affected by opioid use disorders
(OUDs). Comorbid disorders are suspected to increase the risk of opioid-related adverse …

Importance The proportion of patients who develop long-term benzodiazepine use remains
controversial, as do the length of time before long-term use develops and the factors …

As the most common sleep disorder, insomnia seriously affects people's everyday lives.
Phytochemicals have been shown to have excellent sleep-promoting effects. Therefore, this …

The COVID-19 pandemic is producing widespread loss of life, unemployment, and social
isolation that is triggering a mental health crisis. Experts warn there could be record levels of …

Benzodiazepines and z-drugs are primarily indicated for the treatment of sleep disorders
and anxiety symptoms. Their frequent long-term use contrasts with the international …

Background This research was designed to investigate patient-reported and doctor-reported
reasons for the discontinuation of pharmacological treatment in Chinese patients with major …

Benzodiazepines are not indicated for pain control, but they are frequently taken by pain
patients. Indeed, benzodiazepines are among the most widely prescribed drugs on earth …

Objective Patients with chronic insomnia are prone to long-term use of hypnotics. Reported
risk factors include aging, female sex, and comorbid psychiatric disorders. However, most …

In the movie,“Starting Over,” there is a scene in a crowded department store in which an
anxious Burt Reynolds cries out,“Does anyone have a Valium?” When he looked up to see if …