[HTML][HTML] An emerging focus on lipids in extracellular vesicles
T Skotland, K Sagini, K Sandvig, A Llorente - Advanced drug delivery …, 2020 - Elsevier
Extracellular vesicles contain a lipid bilayer membrane that protects the encapsulated
material, such as proteins, nucleic acids, lipids and metabolites, from the extracellular …
material, such as proteins, nucleic acids, lipids and metabolites, from the extracellular …
Native and bioengineered extracellular vesicles for cardiovascular therapeutics
RC de Abreu, H Fernandes… - Nature reviews …, 2020 - nature.com
Extracellular vesicles (EVs) are a heterogeneous group of natural particles that are relevant
to the treatment of cardiovascular diseases. These endogenous vesicles have certain …
to the treatment of cardiovascular diseases. These endogenous vesicles have certain …
Engineered extracellular vesicles with synthetic lipids via membrane fusion to establish efficient gene delivery
YY Jhan, D Prasca-Chamorro, GP Zuniga… - International journal of …, 2020 - Elsevier
The low yield of extracellular vesicle (EV) secretion is a major obstacle for mass production
and limits their potential for clinical applications as a drug delivery platform. Here, we mass …
and limits their potential for clinical applications as a drug delivery platform. Here, we mass …
The future of Extracellular Vesicles as Theranostics–an ISEV meeting report
The utilization of extracellular vesicles (EVs) in clinical theranostics has rapidly advanced in
the past decade. In November 2018, the International Society for Extracellular Vesicles …
the past decade. In November 2018, the International Society for Extracellular Vesicles …
Functional assays to assess the therapeutic potential of extracellular vesicles
VVT Nguyen, KW Witwer, MC Verhaar… - Journal of …, 2020 - Wiley Online Library
An important aspect in the development of extracellular vesicle (EV) therapeutics is
identifying and quantifying the key features defining their identity, purity, sterility, potency …
identifying and quantifying the key features defining their identity, purity, sterility, potency …
[HTML][HTML] Exosomes in head and neck cancer: Roles, mechanisms and applications
Exosomes are extracellular vesicles with a diameter of 30–100 nm that exist stably in
various body fluids, including the blood, cerebrospinal fluid, urine, saliva, and serous cavity …
various body fluids, including the blood, cerebrospinal fluid, urine, saliva, and serous cavity …
[HTML][HTML] Capillary zone electrophoresis of bacterial extracellular vesicles: A proof of concept
M Piotrowska, K Ciura, M Zalewska, M Dawid… - … of Chromatography A, 2020 - Elsevier
The extracellular vesicles (EVs) released by plant pathogens of the Pectobacterium genus
were investigated. The isolates were obtained using differential centrifugation followed by …
were investigated. The isolates were obtained using differential centrifugation followed by …
Challenges of manufacturing mesenchymal stromal cell–derived extracellular vesicles in regenerative medicine
EF Wiest, AC Zubair - Cytotherapy, 2020 - Elsevier
The field of regenerative medicine has expanded greatly in the past decade, with more than
1000 current clinical trials involving mesenchymal stromal cell (MSC) treatment. Multiple …
1000 current clinical trials involving mesenchymal stromal cell (MSC) treatment. Multiple …
Cell-free extracellular vesicles derived from human bone marrow endothelial progenitor cells as potential therapeutics for microvascular endothelium restoration in …
S Garbuzova-Davis, AE Willing, J Ehrhart… - Neuromolecular …, 2020 - Springer
Repairing the damaged blood-CNS-barrier in amyotrophic lateral sclerosis (ALS) is
necessary to prevent entry of detrimental blood-borne factors contributing to motor neuron …
necessary to prevent entry of detrimental blood-borne factors contributing to motor neuron …
Extracellular vesicles as potential prognostic markers of lymphatic dysfunction
Despite significant efforts made to treat cardiovascular disease (CVD), more than half of
cardiovascular events still occur in asymptomatic subjects devoid of traditional risk factors …
cardiovascular events still occur in asymptomatic subjects devoid of traditional risk factors …