Everything you ever wanted to know about PKA regulation and its involvement in mammalian sperm capacitation

CB Graf, C Ritagliati, C Stival, GM Luque… - Molecular and Cellular …, 2020 - Elsevier
Abstract The 3′, 5′-cyclic adenosine monophosphate (cAMP) dependent protein kinase
(PKA) is a tetrameric holoenzyme comprising a set of two regulatory subunits (PKA-R) and …

Regulatory function of praja ring finger ubiquitin ligase 2 mediated by the P2rx3/P2rx7 axis in mouse hippocampal neuronal cells

M Gong, S Ye, WX Li, J Zhang, Y Liu… - … of Physiology-Cell …, 2020 - journals.physiology.org
Praja2 (Pja2), a member of the growing family of mammalian RING E3 ubiquitin ligases, is
reportedly involved in not only several types of cancer but also neurological diseases and …

Glucose deprivation affects the expression of genes encoding cAMP-activated protein kinase and related proteins in U87 glioma cells in ERN1 dependent manner

OO Ratushna - Endocrine Regulations, 2020 - sciendo.com
Objective. The aim of this investigation was to study the expression of genes encoding cAMP-
activated protein kinase catalytic and regulatory A subunits (PRKACA and PRKAR1A) and …

Advances in characterizing recently-identified molecular actions of melatonin: clinical implications

RJ Reiter, R Sharma, SA Rosales-Corral… - … and Systems Approach …, 2020 - Springer
Abstract Melatonin, N-acetyl-5-methoxy-tryptamine, was discovered to be a product of
serotonin metabolism in the mammalian pineal gland where its synthesis is under control of …

Multiple domains in ARHGAP36 regulate PKA degradation and Gli activation

PR Nano, T Kudo, NA Mooney, J Ni, J Demeter… - bioRxiv, 2020 - biorxiv.org
ABSTRACT ARHGAP36 is a Rho GTPase-activating protein (GAP) family member that
contributes to spinal cord development and tumorigenesis. This multidomain protein is …