Do different IgG repertoires play a role in B‐and T‐cell functional modulation during ontogeny? The “hooks without bait” theory

JR Victor - Immunology and Cell Biology, 2020 - Wiley Online Library
The mechanisms by which immunoglobulin (Ig) G can modulate immunity have been
investigated over the past few decades. In the past three years, some studies have …

Natural self-ligand gamma delta T cell receptors (γδTCRs) insight: the potential of induced IgG

TR de Sousa, JR Victor - Vaccines, 2020 - mdpi.com
A γδ T cell acquires functional properties in response to the gamma delta T cell receptor
γδTCR signal strength during its development in the thymus. The elucidation of the potential …

The potential of IgG to induce murine and human thymic maturation of IL-10+ B Cells (B10) revealed in a pilot study

AHS Inoue, AAL Lira, MG De-Oliveira, TR de Sousa… - Cells, 2020 - mdpi.com
Regulatory B (B10) cells can control several inflammatory diseases, including allergies;
however, the origin of peripheral B10 cells is not fully understood, and the involvement of …

IgG from atopic individuals can mediate non-atopic infant thymic and adult peripheral CD8+ TC2 skewing without influence on TC17 or TC22 cells.

T Rodrigues de Sousa… - European Annals of …, 2020 - europepmc.org
The potential of IgG antibodies as allergy regulators has been discussed for decades and
was brought to light that anti-allergen IgG is related to allergy inhibition in children during the …

Preconceptional immunization with an allergen inhibits offspring thymic Th17 cells maturation without influence on Th1 and Th2 cells

MG de Oliveira, FR Sgnotto, TR de Sousa… - European Cytokine …, 2020 - Springer
The mechanisms through which maternal immunization can modulate offspring thymic
maturation of lymphocytes are not fully understood. Here, we aimed to evaluate whether …