A brief history of human disease genetics

M Claussnitzer, JH Cho, R Collins, NJ Cox… - Nature, 2020 - nature.com
A primary goal of human genetics is to identify DNA sequence variants that influence
biomedical traits, particularly those related to the onset and progression of human disease …

Tutorial: a guide to performing polygenic risk score analyses

SW Choi, TSH Mak, PF O'Reilly - Nature protocols, 2020 - nature.com
A polygenic score (PGS) or polygenic risk score (PRS) is an estimate of an individual's
genetic liability to a trait or disease, calculated according to their genotype profile and …

Association between maternal perinatal depression and anxiety and child and adolescent development: a meta-analysis

A Rogers, S Obst, SJ Teague, L Rossen… - JAMA …, 2020 - jamanetwork.com
Importance There is widespread interest in associations between maternal perinatal
depression and anxiety and offspring development; however, to date, there has been no …

Social determinants of pregnancy-related mortality and morbidity in the United States: a systematic review

E Wang, KB Glazer, EA Howell… - Obstetrics & …, 2020 - journals.lww.com
OBJECTIVE: To synthesize the literature on associations between social determinants of
health and pregnancy-related mortality and morbidity in the United States and to highlight …

[PDF][PDF] Dental caries profile and associated risk factors among adolescent school children in an urban South-Indian city

P Reddy, J Krithikadatta, V Srinivasan, S Raghu… - Oral Health Prev …, 2020 - quintpub.com
Purpose: To study the dental caries experience among adolescent school children in
Chennai city using the ICDASII scoring system. The secondary objective was to identify …

Trends in diet quality among youth in the United States, 1999-2016

J Liu, CD Rehm, J Onopa, D Mozaffarian - Jama, 2020 - jamanetwork.com
Importance Prior studies of dietary trends among US youth have evaluated major
macronutrients or only a few foods or have used older data. Objective To characterize trends …

Frailty for perioperative clinicians: a narrative review

DI McIsaac, DB MacDonald, SD Aucoin - Anesthesia & Analgesia, 2020 - journals.lww.com
Frailty is a multidimensional syndrome characterized by decreased reserve and diminished
resistance to stressors. People with frailty are vulnerable to stressors, and exposure to the …

[图书][B] Livsmestring på timeplanen: Rett medisin for elevene?

OJ Madsen - 2020 - books.google.com
Kan skolen lære oss å mestre livet? Fra høsten 2020 kommer folkehelse og livsmestring inn
i læreplanen i den norske skolen. Denne oppdateringen av Kunnskapsløftet er hilst …

Salt and cardiovascular disease: insufficient evidence to recommend low sodium intake

M O'Donnell, A Mente, MH Alderman… - European heart …, 2020 - academic.oup.com
Several blood pressure guidelines recommend low sodium intake (< 2.3 g/day, 100 mmol,
5.8 g/day of salt) for the entire population, on the premise that reductions in sodium intake …

[HTML][HTML] Epidemiology of recovery from alcohol use disorder

JA Tucker, SD Chandler, K Witkiewitz - Alcohol research: current …, 2020 - ncbi.nlm.nih.gov
Almost one-third of the US population meets alcohol use disorder (AUD) criteria on a lifetime
basis. This review provides an overview of recent research on the prevalence and patterns …