The lack of in vitro tissue and organ models capable of mimicking human physiology
severely hinders the development and clinical translation of therapies and drugs with higher …

The epithelial–mesenchymal transition (EMT) is a process by which cells lose epithelial
traits, such as cell–cell adhesion and apico-basal polarity, and acquire migratory and …

Three-dimensional bioprinting of cell-laden hydrogels in a sacrificial support-bath has
recently emerged as a potential solution for fabricating complex biological structures …

Synthetically modified proteins, such as gelatin methacryloyl (GelMA), are growing in
popularity for bioprinting and biofabrication. GelMA is a photocurable macromer that can …

Abstract Two‐photon polymerization (2PP) is a lithography‐based 3D printing method
allowing the fabrication of 3D structures with sub‐micrometer resolution. This work focuses …

Bone marrow (BM) organoids provide powerful tools to study the vital interplay between the
BM microenvironment and resident cells. Current biomaterials, however, are limited in terms …

The mechanics of the extracellular matrix (ECM) have long been known to have important
implications for cancer metastasis and cell migration. An atypical increase in tumor ECM …

Three-dimensional (3D) bioprinting is a highly innovative and promising technology to
render precise positioning of biologics together with living cells and extracellular matrix …

Various cues from the microenvironment in which cells live can regulate cellular functions. In
addition to biochemical cues, increasing evidence has demonstrated that mechanical cues …

The treatment of bone defects with recombinant bone morphogenetic protein‐2 (BMP‐2)
requires high doses precluding broad clinical application. Here, a bioengineering approach …