The role of long noncoding RNAs in hepatocellular carcinoma

Z Huang, JK Zhou, Y Peng, W He, C Huang - Molecular cancer, 2020 - Springer
Hepatocellular carcinoma (HCC) is the most frequent subtype of primary liver cancer and
one of the leading causes of cancer-related death worldwide. However, the molecular …

The role of histone methylation in the development of digestive cancers: a potential direction for cancer management

Y Chen, B Ren, J Yang, H Wang, G Yang… - Signal transduction and …, 2020 - nature.com
Digestive cancers are the leading cause of cancer-related death worldwide and have high
risks of morbidity and mortality. Histone methylation, which is mediated mainly by lysine …

RNA-binding proteins as important regulators of long non-coding RNAs in cancer

K Jonas, GA Calin, M Pichler - International journal of molecular sciences, 2020 - mdpi.com
The majority of the genome is transcribed into pieces of non-(protein) coding RNA, among
which long non-coding RNAs (lncRNAs) constitute a large group of particularly versatile …

Pathophysiological functions of the lncRNA TUG1

C Guo, Y Qi, J Qu, L Gai, Y Shi… - Current pharmaceutical …, 2020 - ingentaconnect.com
Background: Long non-coding RNAs (lncRNAs) with little or no coding capacity are
associated with a plethora of cellular functions, participating in various biological processes …

Long noncoding RNA MALAT1 contributes to sorafenib resistance by targeting miR-140-5p/Aurora-A signaling in hepatocellular carcinoma

L Fan, X Huang, J Chen, K Zhang, Y Gu, J Sun… - Molecular cancer …, 2020 - AACR
Long noncoding RNAs (lncRNA) have been found to play critical roles in tumorigenesis and
the development of various cancers, including hepatocellular carcinoma (HCC). Metastasis …

Role of taurine, its haloamines and its lncRNA TUG1 in both inflammation and cancer progression. On the road to therapeutics?

S Baliou, AM Kyriakopoulos… - International …, 2020 - spandidos-publications.com
For one century, taurine is considered as an end product of sulfur metabolism. In this review,
we discuss the beneficial effect of taurine, its haloamines and taurine upregulated gene 1 …

lncRNA and mechanisms of drug resistance in cancers of the genitourinary system

DA Barth, J Juracek, O Slaby, M Pichler, GA Calin - Cancers, 2020 - mdpi.com
Available systemic treatment options for cancers of the genitourinary system have
experienced great progress in the last decade. However, a large proportion of patients …

LncRNAs in HCV infection and HCV-related liver disease

JP Unfried, P Fortes - International Journal of Molecular Sciences, 2020 - mdpi.com
Long non-coding RNAs (lncRNAs) are transcripts with poor coding capacity that may interact
with proteins, DNA, or other RNAs to perform structural and regulatory functions. The …

Exosomal taurine up-regulated 1 promotes angiogenesis and endothelial cell proliferation in cervical cancer

L Lei, Q Mou - Cancer Biology & Therapy, 2020 - Taylor & Francis
Emerging evidence had highlighted that exosomes could mediate cell-cell communication in
human cancerous development via transferring the various molecular cargos, including long …

Long non-coding RNA TUG1 promotes cell progression in hepatocellular carcinoma via regulating miR-216b-5p/DLX2 axis

Q Dai, J Deng, J Zhou, Z Wang, X Yuan, S Pan… - Cancer cell …, 2020 - Springer
Background Accumulating evidence indicates that the long noncoding RNA taurine
upregulated gene 1 (TUG1) plays a critical role in cancer progression and metastasis …