The role of long noncoding RNAs in hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is the most frequent subtype of primary liver cancer and
one of the leading causes of cancer-related death worldwide. However, the molecular …
one of the leading causes of cancer-related death worldwide. However, the molecular …
The role of histone methylation in the development of digestive cancers: a potential direction for cancer management
Y Chen, B Ren, J Yang, H Wang, G Yang… - Signal transduction and …, 2020 - nature.com
Digestive cancers are the leading cause of cancer-related death worldwide and have high
risks of morbidity and mortality. Histone methylation, which is mediated mainly by lysine …
risks of morbidity and mortality. Histone methylation, which is mediated mainly by lysine …
RNA-binding proteins as important regulators of long non-coding RNAs in cancer
The majority of the genome is transcribed into pieces of non-(protein) coding RNA, among
which long non-coding RNAs (lncRNAs) constitute a large group of particularly versatile …
which long non-coding RNAs (lncRNAs) constitute a large group of particularly versatile …
Pathophysiological functions of the lncRNA TUG1
C Guo, Y Qi, J Qu, L Gai, Y Shi… - Current pharmaceutical …, 2020 - ingentaconnect.com
Background: Long non-coding RNAs (lncRNAs) with little or no coding capacity are
associated with a plethora of cellular functions, participating in various biological processes …
associated with a plethora of cellular functions, participating in various biological processes …
Long noncoding RNA MALAT1 contributes to sorafenib resistance by targeting miR-140-5p/Aurora-A signaling in hepatocellular carcinoma
L Fan, X Huang, J Chen, K Zhang, Y Gu, J Sun… - Molecular cancer …, 2020 - AACR
Long noncoding RNAs (lncRNA) have been found to play critical roles in tumorigenesis and
the development of various cancers, including hepatocellular carcinoma (HCC). Metastasis …
the development of various cancers, including hepatocellular carcinoma (HCC). Metastasis …
Role of taurine, its haloamines and its lncRNA TUG1 in both inflammation and cancer progression. On the road to therapeutics?
S Baliou, AM Kyriakopoulos… - International …, 2020 - spandidos-publications.com
For one century, taurine is considered as an end product of sulfur metabolism. In this review,
we discuss the beneficial effect of taurine, its haloamines and taurine upregulated gene 1 …
we discuss the beneficial effect of taurine, its haloamines and taurine upregulated gene 1 …
lncRNA and mechanisms of drug resistance in cancers of the genitourinary system
Available systemic treatment options for cancers of the genitourinary system have
experienced great progress in the last decade. However, a large proportion of patients …
experienced great progress in the last decade. However, a large proportion of patients …
LncRNAs in HCV infection and HCV-related liver disease
JP Unfried, P Fortes - International Journal of Molecular Sciences, 2020 - mdpi.com
Long non-coding RNAs (lncRNAs) are transcripts with poor coding capacity that may interact
with proteins, DNA, or other RNAs to perform structural and regulatory functions. The …
with proteins, DNA, or other RNAs to perform structural and regulatory functions. The …
Exosomal taurine up-regulated 1 promotes angiogenesis and endothelial cell proliferation in cervical cancer
L Lei, Q Mou - Cancer Biology & Therapy, 2020 - Taylor & Francis
Emerging evidence had highlighted that exosomes could mediate cell-cell communication in
human cancerous development via transferring the various molecular cargos, including long …
human cancerous development via transferring the various molecular cargos, including long …
Long non-coding RNA TUG1 promotes cell progression in hepatocellular carcinoma via regulating miR-216b-5p/DLX2 axis
Q Dai, J Deng, J Zhou, Z Wang, X Yuan, S Pan… - Cancer cell …, 2020 - Springer
Background Accumulating evidence indicates that the long noncoding RNA taurine
upregulated gene 1 (TUG1) plays a critical role in cancer progression and metastasis …
upregulated gene 1 (TUG1) plays a critical role in cancer progression and metastasis …