Practical guidance for the evaluation and management of drug hypersensitivity: specific drugs

AD Broyles, A Banerji, S Barmettler, CM Biggs… - The Journal of Allergy …, 2020 - Elsevier
Allergists and clinical immunologists around the world are increasingly faced with the task of
addressing drug allergy and hypersensitivity due to the increase in drug reactions …

HIV-1 integrase inhibitors: a comparative review of efficacy and safety

KK Scarsi, JP Havens, AT Podany, SN Avedissian… - Drugs, 2020 - Springer
The newest class of antiretrovirals for all persons living with HIV are the integrase strand
transfer inhibitors (INSTIs). Since 2007, five INSTIs have been introduced: raltegravir …

Comparison of overall and comorbidity-free life expectancy between insured adults with and without HIV infection, 2000-2016

JL Marcus, WA Leyden, SE Alexeeff… - JAMA network …, 2020 - jamanetwork.com
Importance Antiretroviral therapy (ART) has improved life expectancy for individuals with HIV
infection, but recent data comparing life span and comorbidity-free years by HIV status are …

Global prevalence and burden of HIV-associated neurocognitive disorder: a meta-analysis

Y Wang, M Liu, Q Lu, M Farrell, JM Lappin, J Shi, L Lu… - Neurology, 2020 - AAN Enterprises
Objective To characterize the prevalence and burden of HIV-associated neurocognitive
disorder (HAND) and assess associated factors in the global population with HIV. Methods …

Outcomes of COVID-19 related hospitalisation among people with HIV in the ISARIC WHO Clinical Characterisation Protocol UK Protocol: prospective observational …

AM Geretti, AJ Stockdale, SH Kelly, M Cevik, S Collins… - MedRxiv, 2020 - medrxiv.org
Background. There is conflicting evidence about how HIV infection influences COVID-19.
We compared the presentation characteristics and outcomes of people with and without HIV …

Potency and timing of antiviral therapy as determinants of duration of SARS-CoV-2 shedding and intensity of inflammatory response

A Goyal, EF Cardozo-Ojeda, JT Schiffer - Science advances, 2020 - science.org
To affect the COVID-19 pandemic, lifesaving antiviral therapies must be identified. The
number of clinical trials that can be performed is limited. We developed mathematical …

Cognitive disorders in people living with HIV

A Winston, S Spudich - The Lancet HIV, 2020 - thelancet.com
High rates of cognitive disorders in antiretroviral-treated people living with HIV have been
described worldwide. The exact prevalence of such cognitive disorders is determined by the …

[HTML][HTML] Highly active antiretroviral therapy (HAART)

JS Eggleton, S Nagalli - 2020 - europepmc.org
Objectives: Describe the treatment considerations for patients with HIV. Identify the most
common adverse events associated with highly active antiretroviral therapy (HAART) …

What do the Universal Test and Treat trials tell us about the path to HIV epidemic control?

D Havlir, S Lockman, H Ayles… - Journal of the …, 2020 - Wiley Online Library
Introduction Achieving HIV epidemic control globally will require new strategies to
accelerate reductions in HIV incidence and mortality. Universal test and treat (UTT) was …

[HTML][HTML] Optimizing treatment for adults with HIV/AIDS in China: successes over two decades and remaining challenges

W Cao, E Hsieh, T Li - Current HIV/AIDS Reports, 2020 - Springer
Abstract Purpose of Review The introduction of the National Free Antiretroviral Therapy
Program (NFATP) in 2003 by the China National Center for AIDS/STD Control and …