Vimentin is an intermediate filament protein that plays key roles in integration of cytoskeletal
functions, and therefore in basic cellular processes such as cell division and migration …

Viruses reshape the organization of the cell interior to achieve different steps of their cellular
cycle. Particularly, viral replication and assembly often take place in viral factories where …

POTENTIAL CONFLICT OF INTEREST: The University of Virginia has filed patent
applications related to new technologies for the rapid production of vaccines, and Dr …

Coronavirus disease 2019 (COVID-19) is a severe acute respiratory syndrome (SARS) in
humans that is caused by SARS-associated coronavirus type 2 (SARS-CoV-2). In the …

We and others propose vimentin as a possible cellular target for the treatment of COVID-19.
This innovative idea is so recent that it requires further attention and debate. The significant …

We report that several viruses from the human enterovirus group B cause massive vimentin
rearrangements during lytic infection. Comprehensive studies suggested that viral protein …

Understanding the systems biology approaches for promoting the development of new
therapeutic drugs is attaining importance nowadays. The threat of COVID-19 outbreak …

Arginine synergistically inactivates enveloped viruses at a pH or temperature that does little
harm to proteins, making it a desired process for therapeutic protein manufacturing …

Nonstructural protein 3A of foot-and-mouth disease virus (FMDV) is a partially conserved
protein of 153 amino acids that is in most FMDVs examined to date, and it plays important …

As a live biologic agent, oncolytic vaccinia virus has the ability to target and selectively
amplify at tumor sites. We have previously reported that deletion of thymidine kinase and …