Dermatomyositis: an update on diagnosis and treatment

GA Cobos, A Femia, RA Vleugels - American Journal of Clinical …, 2020 - Springer
Dermatomyositis is a rare inflammatory disease with characteristic cutaneous findings and
varying amounts of systemic involvement. Patients may present with skin disease alone …

[HTML][HTML] Therapeutic options for the treatment of interstitial lung disease related to connective tissue diseases. A narrative review

C Vacchi, M Sebastiani, G Cassone, S Cerri… - Journal of Clinical …, 2020 - mdpi.com
Interstitial lung disease (ILD) is one of the most serious pulmonary complications of
connective tissue diseases (CTDs) and it is characterized by a deep impact on morbidity and …

Recommendations for the treatment of anti-melanoma differentiation-associated gene 5-positive dermatomyositis-associated rapidly progressive interstitial lung …

F Romero-Bueno, PD Del Campo… - Seminars in arthritis and …, 2020 - Elsevier
Objectives The study aimed to develop evidence-based recommendations for the treatment
of rapidly progressive interstitial lung disease (RPILD) associated with the anti-Melanoma …

[HTML][HTML] Predictors and mortality of rapidly progressive interstitial lung disease in patients with idiopathic inflammatory myopathy: a series of 474 patients

Y Li, X Gao, Y Li, X Jia, X Zhang, Y Xu, Y Gan… - Frontiers in …, 2020 - frontiersin.org
Objective: This study was conducted to identify the characteristics and prognosis of rapidly
progressive interstitial lung disease (RP-ILD) in idiopathic inflammatory myopathy (IIM) and …

Recognition and management of myositis-associated rapidly progressive interstitial lung disease

R Jablonski, S Bhorade, ME Strek, J Dematte - Chest, 2020 - Elsevier
Idiopathic inflammatory myopathies are autoimmune processes that are characterized by
skeletal muscle inflammation. The lung is the most commonly involved extramuscular organ …

[HTML][HTML] Ultra-low dose rituximab as add-on therapy in anti-MDA5-positive patients with polymyositis/dermatomyositis associated ILD

M Mao, S Xia, B Guo, W Qian, Z Zheng, X Peng… - Respiratory …, 2020 - Elsevier
Objectives To evaluate the efficacy and safety of ultra-low dose (100 mg) rituximab (RTX)
administration in anti-melanoma differentiation-associated gene 5 (MDA5) positive patients …

Anti-MDA5 juvenile idiopathic inflammatory myopathy: a specific subgroup defined by differentially enhanced interferon-α signalling

I Melki, H Devilliers, C Gitiaux, V Bondet, D Duffy… - …, 2020 - academic.oup.com
Objectives JDM and juvenile overlap myositis represent heterogeneous subtypes of juvenile
idiopathic inflammatory myopathy (JIIM). Chronic evolution can occur in up to 60% of cases …

Combined immunosuppressive therapy provides favorable prognosis and increased risk of cytomegalovirus reactivation in anti‐melanoma differentiation‐associated …

KM Matsuda, A Yoshizaki, A Kuzumi… - The Journal of …, 2020 - Wiley Online Library
Anti‐melanoma differentiation‐associated gene 5 (MDA5) antibody (Ab) is myositis‐specific
autoantibody associated with rapidly progressive interstitial lung disease (ILD) and poor …

Current understanding and recent advances in myositis-specific and-associated autoantibodies detected in patients with dermatomyositis

T Gono, M Kuwana - Expert Review of Clinical Immunology, 2020 - Taylor & Francis
Introduction: Dermatomyositis (DM) is characterized by skin lesions, such as heliotrope rash
and Gottron's papules/sign, and skeletal myopathy. Patients with DM often have arthritis …

Insights into pathogenesis and clinical implications in myositis-associated interstitial lung diseases

T Yanagihara, Y Inoue - Current Opinion in Pulmonary Medicine, 2020 - journals.lww.com
The genetic differences in the myositis-susceptible loci may explain the heterogeneous
phenotypes and treatment responses in myositis-associated ILD. The understanding of …
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