Vascular disease is a progressive inflammatory condition fuelled by an unhealthy lifestyle of
physical inactivity, cholesterol-rich diet, and smoking. Together with endogenous factors …

Extracellular vesicles are heterogeneous populations of naturally occurring secreted small
vesicles. EVs function as signaling platforms to facilitate intracellular communication, which …

Atherosclerosis is a chronic inflammatory disease that is characterized by the formation of
lipid rich plaques in the wall of medium to large sized arteries. Atherothrombosis represents …

Beyond their crucial role in hemostasis, platelets are increasingly recognized as regulators
of inflammation. Via modulation of the immune system by direct and indirect interactions with …

Background Diabetes mellitus is characterized by chronic vascular inflammation leading to
pathological expression of the thrombogenic full length (fl) tissue factor (TF) and its isoform …

A confluence of technological advances in genetic manipulation and molecular-based
fluorescence imaging has led to the widespread adoption of laser injury models to study …

Immune thrombocytopenia (ITP) patients have thrombocytopenia and increased bleeding
risk, but, conversely, they also have increased thrombotic risk which appears to be …

The coexistence of bleeding and thrombosis in patients with chronic kidney disease (CKD)
is frequent and poorly understood. Mouse models are essential to understand complications …

Background Microvesicles are cell membrane–derived vesicles that have been shown to
augment inflammation. Specifically, monocyte‐derived microvesicles (MDMVs), which can …

Ekstrensek pıhtılaşma sisteminde bazı proteinlere postranslasyonel modifikasyonla
karboksil grubu bağlanır. Bu reaksiyon için K vitamini gereklidir. Çünkü karboksilazların …